BMY-7,378
BMY-7,378 is a chemical compound that belongs to the class of benzodiazepine derivatives. It is a potent and selective agonist at the GABAA receptor, and has anxiolytic and anticonvulsant properties.
Chemistry[edit | edit source]
BMY-7,378 is a benzodiazepine derivative, which means it is structurally related to benzodiazepines, a class of drugs that includes diazepam and alprazolam. However, BMY-7,378 has a unique chemical structure that distinguishes it from other benzodiazepines.
Pharmacology[edit | edit source]
BMY-7,378 acts as an agonist at the GABAA receptor, the most widespread inhibitory receptor in the brain. By enhancing the effects of GABA, BMY-7,378 can reduce neuronal excitability and produce anxiolytic and anticonvulsant effects.
Therapeutic Use[edit | edit source]
Due to its anxiolytic and anticonvulsant properties, BMY-7,378 has potential therapeutic use in the treatment of conditions such as anxiety disorders and epilepsy. However, further research is needed to fully understand its efficacy and safety profile.
Research[edit | edit source]
Research on BMY-7,378 is ongoing, with studies focusing on its pharmacological properties and potential therapeutic applications. These studies are contributing to our understanding of the GABAA receptor and the role it plays in various neurological and psychiatric disorders.
See Also[edit | edit source]
Benzodiazipines[edit source]
- Alprazolam
- Chlordiazepoxide
- Diazepam (Oral)
- Estazolam
- Flurazepam
- Lorazepam
- Midazolam
- Oxazepam
- Quazepam
- Temazepam
- Triazolam
Anticonvulsants Drugs[edit source]
Drug class for BMY-7,378[edit source]
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Contributors: Prab R. Tumpati, MD
