Dermal fibroblast

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Dermal fibroblasts are a type of cell that resides in the dermis layer of the skin. They play a crucial role in maintaining skin homeostasis and in wound healing.

Etymology[edit | edit source]

The term "fibroblast" is derived from the Greek words "fibra" meaning fiber and "blastos" meaning germ.

Function[edit | edit source]

Dermal fibroblasts are responsible for producing the extracellular matrix in the dermis, which provides structural support to the skin. They also play a role in the production of collagen, elastin, and fibronectin, which are essential for skin elasticity and strength.

In response to skin injury, dermal fibroblasts migrate to the wound site and produce growth factors that promote the proliferation of other cells involved in wound healing. They also differentiate into myofibroblasts, which are involved in wound contraction.

Related Terms[edit | edit source]

See Also[edit | edit source]

Dermal fibroblast Resources
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Contributors: Prab R. Tumpati, MD