Dydrogesterone
(Redirected from Gynorest)
Dydrogesterone is a synthetic, orally active progestogen drug that is used primarily for the treatment of disorders linked to progesterone deficiency. Progesterone is a natural hormone that plays a vital role in the menstrual cycle and in maintaining the early stages of pregnancy.
Mechanism of Action[edit | edit source]
Upon administration, dydrogesterone exhibits high affinity for progesterone receptors. By binding to these receptors, it helps regulate the growth and normal shedding of the uterine lining during the menstrual cycle. Interestingly, dydrogesterone does not appear to bind to other types of hormone receptors, such as androgenic, estrogenic, glucocorticoid, or mineralocorticoid receptors. This specificity may reduce the risk of unwanted side effects that are sometimes associated with other hormone therapies.
Clinical Use[edit | edit source]
Dydrogesterone is used in a variety of clinical situations related to progesterone deficiency. These include:
- Dysmenorrhea: Also known as painful periods, this condition can be alleviated by dydrogesterone's ability to regulate the menstrual cycle.
- Endometriosis: Dydrogesterone can help manage the symptoms of endometriosis, a condition where the tissue that normally lines the uterus grows outside the uterus.
- Miscarriage Prevention: In cases where miscarriages are linked to progesterone deficiency, dydrogesterone can be used to support the early stages of pregnancy.
- Hormone Replacement Therapy (HRT): Dydrogesterone is often used in conjunction with estrogen in post-menopausal women to prevent the overgrowth of the uterine lining that can be caused by estrogen alone.
Current Research[edit | edit source]
Active clinical trials are ongoing to further understand the potential uses of dydrogesterone in various clinical scenarios.
References[edit | edit source]
- Mauvais-Jarvis P, Kuttenn F, Gompel A (2004). "Antiestrogen action of progesterone in breast tissue". Breast Cancer Res Treat. 24 (3): 270–6.
- Bouchard P (2000). "Dydrogesterone in combination with estrogens for postmenopausal women". Climacteric. 3 (3): 175–82.
| Dydrogesterone Resources | |
|---|---|
|
 |
| Dydrogesterone Resources | |
|---|---|
|
|
Search WikiMD
Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro / Zepbound) available.
Advertise on WikiMD
|
WikiMD's Wellness Encyclopedia |
| Let Food Be Thy Medicine Medicine Thy Food - Hippocrates |
Translate this page: - East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
தமிழ்,
తెలుగు,
Urdu,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
বাংলা
European
español,
Deutsch,
français,
Greek,
português do Brasil,
polski,
română,
русский,
Nederlands,
norsk,
svenska,
suomi,
Italian
Middle Eastern & African
عربى,
Turkish,
Persian,
Hebrew,
Afrikaans,
isiZulu,
Kiswahili,
Other
Bulgarian,
Hungarian,
Czech,
Swedish,
മലയാളം,
मराठी,
ਪੰਜਾਬੀ,
ગુજરાતી,
Portuguese,
Ukrainian
Medical Disclaimer: WikiMD is not a substitute for professional medical advice. The information on WikiMD is provided as an information resource only, may be incorrect, outdated or misleading, and is not to be used or relied on for any diagnostic or treatment purposes. Please consult your health care provider before making any healthcare decisions or for guidance about a specific medical condition. WikiMD expressly disclaims responsibility, and shall have no liability, for any damages, loss, injury, or liability whatsoever suffered as a result of your reliance on the information contained in this site. By visiting this site you agree to the foregoing terms and conditions, which may from time to time be changed or supplemented by WikiMD. If you do not agree to the foregoing terms and conditions, you should not enter or use this site. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates Wikipedia, licensed under CC BY SA or similar.
Contributors: Prab R. Tumpati, MD
