IgA vasculitis

IgA vasculitis, formerly known as Henoch-Schönlein purpura, is a type of vasculitis that affects the small blood vessels in the skin, joints, intestines, and kidneys. It is the most common form of childhood vasculitis and is characterized by the deposition of immunoglobulin A (IgA) in the affected organs.

Signs and Symptoms

The most common symptom of IgA vasculitis is a rash, known as purpura, which appears as red or purple spots on the skin. Other symptoms can include joint pain, abdominal pain, and kidney problems. The severity of symptoms can vary greatly from person to person.

Causes

The exact cause of IgA vasculitis is unknown, but it is thought to be an abnormal response of the immune system. It often occurs after an infection, such as a throat or respiratory infection.

Diagnosis

Diagnosis of IgA vasculitis is based on the presence of the characteristic rash, along with at least one other symptom. Blood tests and urine tests may be used to check for signs of kidney involvement. In some cases, a skin or kidney biopsy may be needed to confirm the diagnosis.

Treatment

Treatment for IgA vasculitis is aimed at relieving symptoms and preventing complications. This can include medications to reduce inflammation and pain, and in severe cases, medications to suppress the immune system.

Prognosis

The prognosis for IgA vasculitis is generally good, with most people making a full recovery. However, in some cases, kidney damage can occur, which can lead to long-term health problems.

See Also

• Vasculitis
• Immunoglobulin A
• Purpura

IgA vasculitis Resources
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