Reiter's disease

Reiter's disease, also known as Reactive arthritis, is a type of inflammatory arthritis that develops in response to an infection in another part of the body. This condition is characterized by the classic triad of symptoms: arthritis, urethritis, and conjunctivitis.

Feet-Reiters syndrome

Etiology

Reiter's disease is typically triggered by a bacterial infection in the gastrointestinal tract or the genitourinary tract. The most common bacteria associated with this condition are Chlamydia trachomatis, Salmonella, Shigella, Yersinia, and Campylobacter.

Symptoms

The primary symptoms of Reiter's disease are inflammation and pain in the joints, particularly the knees, ankles, and feet. Other symptoms may include inflammation of the urethra, resulting in a burning sensation during urination, and inflammation of the eye, leading to redness, pain, and blurred vision. Some patients may also develop skin rashes and mouth ulcers.

Diagnosis

Diagnosis of Reiter's disease is primarily based on the clinical presentation of the triad of symptoms. Laboratory tests may be conducted to identify the presence of HLA-B27, a genetic marker associated with the disease. Imaging studies such as X-rays may be used to assess the extent of joint damage.

Treatment

Treatment for Reiter's disease primarily involves managing the symptoms and includes nonsteroidal anti-inflammatory drugs (NSAIDs), corticosteroids, and immunosuppressive drugs. In cases where the disease is triggered by a bacterial infection, antibiotics may be prescribed.

Prognosis

The prognosis for Reiter's disease varies. Some individuals may recover completely within six months, while others may experience recurrent episodes of arthritis and related symptoms.

Epidemiology

Reiter's disease affects men more frequently than women, and is most common in individuals aged 20 to 40. The disease is also more prevalent in individuals who carry the HLA-B27 gene.

See also

• Arthritis
• Inflammatory diseases
• Autoimmune diseases