Coronary computed tomographic angiography
Coronary Computed Tomographic Angiography[edit | edit source]
Coronary Computed Tomographic Angiography (CCTA) is a non-invasive imaging technique used to visualize the coronary arteries of the heart. It employs advanced computed tomography (CT) technology to obtain high-resolution images of the coronary vessels, allowing for the assessment of coronary artery disease (CAD).
History[edit | edit source]
The development of CCTA began in the late 20th century with the advent of multi-detector CT (MDCT) technology. The first clinical applications of CCTA were reported in the early 2000s, and since then, it has become an important tool in the diagnosis and management of CAD.
Indications[edit | edit source]
CCTA is primarily indicated for patients with suspected coronary artery disease, particularly those with intermediate risk. It is used to:
- Evaluate chest pain of uncertain origin.
- Assess coronary artery anomalies.
- Plan for coronary interventions or surgeries.
- Evaluate graft patency in patients with previous coronary artery bypass grafting.
Procedure[edit | edit source]
The CCTA procedure involves the following steps: 1. Patient Preparation: Patients may be asked to fast for a few hours before the scan. Beta-blockers may be administered to lower heart rate for optimal imaging. 2. Contrast Administration: An iodine-based contrast agent is injected intravenously to enhance the visibility of coronary arteries. 3. Image Acquisition: The patient lies on a CT table, and the scanner acquires images of the heart during a single breath-hold. 4. Image Reconstruction: Advanced software reconstructs the images, allowing for 3D visualization of the coronary arteries.
Advantages[edit | edit source]
- Non-invasive: Unlike traditional coronary angiography, CCTA does not require catheterization.
- High Sensitivity and Specificity: CCTA provides detailed images that can accurately detect coronary artery stenosis.
- Rapid: The entire procedure can be completed in a short time, often within 30 minutes.
Limitations[edit | edit source]
- Radiation Exposure: Although modern techniques have reduced radiation doses, CCTA still involves exposure to ionizing radiation.
- Contrast Reactions: There is a risk of allergic reactions to the contrast agent.
- Limited Functional Information: CCTA provides anatomical but not functional information about blood flow.
Comparison with Other Modalities[edit | edit source]
CCTA is often compared with other imaging modalities such as invasive coronary angiography, stress testing, and magnetic resonance imaging (MRI). Each modality has its own advantages and limitations, and the choice depends on the clinical scenario.
Also see[edit | edit source]
- Coronary artery disease
- Computed tomography
- Invasive coronary angiography
- Magnetic resonance imaging
Cardiovascular disease A-Z
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