Functioning tumor
Functioning tumor
A functioning tumor is a type of tumor that produces hormones or other substances that can cause specific symptoms or syndromes in the body. These tumors are often found in endocrine organs such as the pituitary gland, adrenal glands, pancreas, and thyroid gland. The overproduction of hormones by functioning tumors can lead to a variety of health issues and medical conditions.
Types of Functioning Tumors:
1. Pituitary Tumors: Pituitary tumors are growths that develop in the pituitary gland, a small gland located at the base of the brain. These tumors can cause an overproduction of hormones such as prolactin, growth hormone, adrenocorticotropic hormone (ACTH), and thyroid-stimulating hormone (TSH). Common pituitary tumors include prolactinomas, acromegaly, Cushing's disease, and thyroid-stimulating hormone-secreting tumors.
2. Adrenal Tumors: Adrenal tumors can occur in the adrenal glands, which are located on top of each kidney. These tumors can produce excess cortisol, aldosterone, or adrenaline, leading to conditions such as Cushing's syndrome, primary aldosteronism, and pheochromocytoma.
3. Pancreatic Tumors: Pancreatic tumors can be either functional or non-functional. Functional pancreatic tumors, such as insulinomas, gastrinomas, glucagonomas, and VIPomas, produce hormones that can cause symptoms related to blood sugar levels, digestion, and electrolyte balance.
4. Thyroid Tumors: Thyroid tumors can be classified as either benign or malignant. Functioning thyroid tumors, such as toxic adenomas and toxic multinodular goiters, can lead to hyperthyroidism and its associated symptoms.
Symptoms of Functioning Tumors:
The symptoms of functioning tumors vary depending on the type of tumor and the hormones it produces. Common symptoms may include:
- Weight gain or weight loss
- High blood pressure
- Fatigue
- Muscle weakness
- Mood changes
- Irregular menstrual periods
- Excessive sweating
- Changes in skin texture
- Digestive issues
Diagnosis and Treatment:
Diagnosing functioning tumors often involves a combination of blood tests, imaging studies (such as CT scans or MRIs), and biopsy procedures. Treatment options for functioning tumors may include surgery, radiation therapy, chemotherapy, hormone therapy, and targeted drug therapy.
It is important for individuals with suspected functioning tumors to seek medical attention promptly to receive an accurate diagnosis and appropriate treatment.
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Contributors: Prab R. Tumpati, MD