Vectical

What is Vectical?

Vectical (calcitriol ointment) is a vitamin D analog used to treat mild to moderate plaque psoriasis.

Calcitriol

Calcitriol3Dan

What are the uses of this medicine?

• VECTICAL (calcitriol ointment) is a prescription medicine used on the skin (topical) to treat mild to moderate plaque psoriasis in adults and children 2 years and older.

Limitations of Use:

• It is not known if VECTICAL Ointment is safe and effective in children under 2 years of age.
• It is not known if VECTICAL Ointment is safe and effective in people with known or suspected problems with calcium metabolism.

How does this medicine work?

• The mechanism of action of calcitriol in the treatment of psoriasis has not been established.

Who Should Not Use this medicine ?

Limitations of Use:

• It is not known if VECTICAL Ointment is safe and effective in children under 2 years of age.
• It is not known if VECTICAL Ointment is safe and effective in people with known or suspected problems with calcium metabolism.

What drug interactions can this medicine cause?

• No formal drug interaction studies have been conducted with VECTICAL.

Is this medicine FDA approved?

• Initial U.S. Approval: 1978

How should this medicine be used?

Recommended dosage: Adults:

• The maximum weekly dose should not exceed 200 grams.

Pediatrics:

• 2 to 6 years of age: the maximum weekly dose should not exceed 100 grams.
• 7 years of age and older: the maximum weekly dose should not exceed 200 grams.

Administration:

• Apply VECTICAL Ointment to the affected areas 2 times each day in the morning and evening.
• Adults and children 7 years of age and older should not use more than 200 grams in 1 week.
• Children 2 to 6 years of age should not use more than 100 grams in 1 week.
• Avoid applying VECTICAL Ointment to your eyes, lips, or facial skin.
• Apply only enough VECTICAL Ointment to cover your affected skin area.
• You should not cover the treated area(s) with a waterproof (occlusive) bandage or overdosage may occur.
• Gently rub VECTICAL Ointment into the affected area until it disappears into your skin.
• Wash your hands after using VECTICAL Ointment, unless you are using the medicine to treat your hands.

What are the dosage forms and brand names of this medicine?

This medicine is available in fallowing doasage form:

• As Ointment, 3 mcg/g

This medicine is available in fallowing brand namesː

• VECTICAL

What side effects can this medication cause?

The most common side effects of this medicine include:

• increased urine calcium level
• itching
• skin discomfort

VECTICAL Ointment may cause serious side effects, including:

• Too much calcium in your blood (hypercalcemia).

What special precautions should I follow?

• In controlled clinical trials hypercalcemia was observed in subjects exposed to VECTICAL Ointment. If aberrations in parameters of calcium metabolism are noted discontinue VECTICAL Ointment until these normalize. Increased absorption may occur with occlusive use.
• VECTICAL Ointment should be used with caution in patients receiving medications known to increase the serum calcium level, such as thiazide diuretics, and in patients receiving calcium supplements or high doses of vitamin D.
• Avoid use of more than 100 grams per week in patients ages 2-6 years and use of more than 200 grams per week in patients ages 7 years and older.
• Instruct patients to report any signs of adverse reactions to their physician.
• Avoid contact with eyes, lips, and facial skin.
• Advise breastfeeding women not to apply VECTICAL Ointment directly to the nipple and areola to avoid direct infant exposure.

What to do in case of emergency/overdose?

• Topically applied calcitriol can be absorbed in sufficient amounts to produce systemic effects.

Can this medicine be used in pregnancy?

• It is not known if VECTICAL Ointment will harm your unborn baby.

Can this medicine be used in children?

• It is not known if VECTICAL Ointment is safe and effective in children under 2 years of age.

What are the active and inactive ingredients in this medicine?

• Active ingredient: calcitriol
• Inactive ingredients: mineral oil, dl-α-tocopherol, and white petrolatum.

Who manufactures and distributes this medicine?

Manufactured by: G. Production Inc. Baie d’Urfé, Canada

What should I know about storage and disposal of this medication?

• Store VECTICAL Ointment at room temperature between 68°F to 77°F (20°C to 25°C).
• Do not freeze or refrigerate VECTICAL Ointment.

• Dailymed label info on Vectical
• FDA Vectical

Vectical Resources
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