Villoglandular adenocarcinoma of the cervix
| Villoglandular adenocarcinoma of the cervix | |
|---|---|
| Villoglandular adenocarcinoma - low mag.jpg | |
| Micrograph of a villoglandular adenocarcinoma the cervix. H&E stain. | |
| Synonyms | Villoglandular papillary adenocarcinoma, papillary villoglandular adenocarcinoma, well-differentiated villoglandular adenocarcinoma (VGA)
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| Specialty | Pathology, gynecology
|
Villoglandular adenocarcinoma of the cervix is a rare type of cervical cancer that, in relation to other cervical cancers, is typically found in younger women and has a better prognosis.[1]
A similar lesion, villoglandular adenocarcinoma of the endometrium, may arise from the inner lining of the uterus, the endometrium.[2]
Signs and symptoms[edit]
The signs and symptoms are similar to other cervical cancers and may include post-coital bleeding and/or pain during intercourse (dyspareunia). Early lesions may be completely asymptomatic.
Cause[edit]
![[icon]](/wiki/File:Wiki_letter_w_cropped.svg){kind=small} | This section is empty. You can help by adding to it. (August 2017) |
Diagnosis[edit]
The diagnosis is based on tissue examination, e.g. biopsy.
The name of the lesion describes it microscopic appearance. It has nipple-like structures with fibrovascular cores (papillae) that are long in relation to their width (villus-like), which are covered with a glandular pseudostratified columnar epithelium.
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Very low mag.
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Intermed. mag.
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Very high mag.
Treatment[edit]
The treatment is dependent on the stage. As the prognosis of this tumour is usually good, fertility sparing approaches (conization, cervicectomy) may be viable treatment options.
See also[edit]
References[edit]
- ↑ "Villoglandular papillary adenocarcinoma of the uterine cervix: a diagnostic challenge.".Acta Obstet Gynecol Scand.2009;88(3)
- 355–8.doi:10.1080/00016340902730359.
- ↑ "Villoglandular adenocarcinoma of the endometrium: a clinicopathologic study of 61 cases: a gynecologic oncology group study.".Am J Surg Pathol.Nov 1998;22(11)
- 1379–85.doi:10.1097/00000478-199811000-00008.
External links[edit]
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