Second-line therapy

Second-line therapy refers to the treatment that is given when initial therapy (first-line therapy) does not work, or stops working. This term is commonly used in the treatment of cancer and tuberculosis.

Overview

In the context of cancer, second-line therapy is the treatment recommended when the cancer does not respond to the first-line therapy, or when it comes back after treatment. This could involve a different type of chemotherapy, radiation therapy, or surgery.

In the case of tuberculosis, second-line drugs are used when the bacteria that cause TB have become resistant to first-line drugs. These drugs are often more expensive, have more side effects, and must be taken for a longer period of time.

Second-line therapy in cancer treatment

In cancer treatment, the choice of second-line therapy depends on many factors, including the type and stage of cancer, the patient's overall health, and the types of treatments the patient has already received. The goal of second-line therapy is to control the growth of the cancer, prolong the patient's life, and manage any symptoms or side effects.

Second-line therapy in tuberculosis treatment

In tuberculosis treatment, second-line drugs are used when the bacteria that cause TB have become resistant to first-line drugs. These drugs are often more expensive, have more side effects, and must be taken for a longer period of time. The World Health Organization (WHO) has classified second-line drugs into two groups: Group A includes the most effective second-line drugs, and Group B includes the next most effective drugs.

See also

• First-line therapy
• Cancer treatment
• Tuberculosis treatment

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