Tadalifil

What Is Tadalifil

Tadalafil (Cialis) is a phosphodiesterase 5 (PDE5) inhibitor used for treatment of men who experience difficulty having and maintaining an erection (impotence).

What are the uses of this medicine?

This medicine is indicated for the treatment of:

• Erectile dysfunction (ED)
• The signs and symptoms of benign prostatic hyperplasia (BPH) which include difficulty urinating (hesitation, dribbling, weak stream, and incomplete bladder emptying), painful urination, and urinary frequency and urgency in adult men.

How does Tadalafil work?

• Tadalafil works by enhancing the effects of one of the chemicals the body normally releases into the penis during sexual arousal.
• This allows an increase of blood flow into the penis.
• An erection is the result of an increase in blood flow into certain internal areas of the penis.

Who Should Not Use Tadalifil ?

• Cialis should not be used by patients taking nitrates (such as nitroglycerin tablets or patches) because the combination of these with Cialis could significantly lower blood pressure and lead to fainting or even death in some men.

Is this medicine FDA approved

• Tadalafil was approved for medical use in the United States in 2003.
• It is available as a generic medication in the United States and United Kingdom.
• In 2017, it was the 282nd most commonly prescribed medication in the United States, with more than one million prescriptions.

How should this medicine be used?

• Cialis is taken orally before sexual activity, not more than once daily.
• Cialis may be taken with or without food.
• In some patients, the dose strength and maximum frequency of use may be adjusted.
• For more detailed information consult with your health care provider.

What are the dosage forms and brand names of this medicine?

• Cialis will be available as oral tablets in 5mg, 10mg and 20mg strengths.

This medicine is available in following brand names:

• Adcirca®
• Cialis®

What side effects can this medication cause?

Common possible side effects of Tadalafil include:

• headache
• indigestion
• back pain
• muscle pain
• flushing
• stuffy nose

Patients who get back pain and muscle aches usually get them 12 to 24 hours after taking Cialis and these usually go away by themselves within 48 hours. A small number of patients taking Cialis also reported abnormal vision.

Adverse reactions may include:

• Dyspepsia
• Myalgia
• Nasal congestion
• Pain in limb

What special precautions should I follow?

• CIALIS can cause your blood pressure to drop suddenly to an unsafe level if it is taken with any nitrate medication. You could get dizzy, faint or have a heart attack or stroke.
• Tell your healthcare provider that you take Cialis. If you need emergency medical care for a heart problem, it will be important for your health care provider to know when you last took Cialis.
• After taking a single tablet, some of the active ingredient of Cialis remains in your body for more than 2 days. The active ingredient can remain longer if you have problems with your kidneys or liver, or you are taking certain other medications.
• Physicians should discuss with patients the potential for CIALIS to augment the blood-pressure-lowering effect of alpha-blockers and antihypertensive medications.

What to do in case of emergency/overdose?

• In cases of overdose, standard supportive measures should be adopted as required.
• Hemodialysis contributes negligibly to tadalafil elimination.

Can this medicine be used in pregnency?

• Tadalafil tablets are not indicated for use in females.

What should I know about storage and disposal of this medication?

• Store at 20° to 25°C (68° to 77°F).
• Keep this and all medications out of the reach of children.

• Dailymed label info on Tadalifil
• FDA Tadalifil

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