Withdrawn drugs

• Adderall XR is a withdrawn drug. The year of withdrawal was 2005, countries it was withdrawn in include Canada, reason(s) for withdrawal include Risk of stroke The ban was later lifted because the death rate among those taking Adderall XR was determined to be no greater than those not taking Adderall.
• Alatrofloxacin is a withdrawn drug. The year of withdrawal was 2006, countries it was withdrawn in include Worldwide, reason(s) for withdrawal include Serious liver injury leading to liver transplant or death.
• Alclofenac is a withdrawn drug. The year of withdrawal was 1979, countries it was withdrawn in include UK, reason(s) for withdrawal include Vasculitis
• Alosetron (Lotronex) is a withdrawn drug. The year of withdrawal was 2000, countries it was withdrawn in include US, reason(s) for withdrawal include Serious gastrointestinal adverse events; ischemic colitis; severe constipation. Reintroduced 2002 on a restricted basis[citation needed]
• Alpidem (Ananxyl) is a withdrawn drug. The year of withdrawal was 1995, countries it was withdrawn in include Worldwide, reason(s) for withdrawal include Not approved in the US, withdrawn in France in 1994 and the rest of the market in 1995 because of rare but serious hepatotoxicity.
• Althesin (Alphaxolone amineptine + Alphadolone) is a withdrawn drug. The year of withdrawal was 1984, countries it was withdrawn in include France, Germany, UK, reason(s) for withdrawal include Anaphylaxis.
• Amineptine (Survector) is a withdrawn drug. The year of withdrawal was 1999, countries it was withdrawn in include France, US, reason(s) for withdrawal include Hepatotoxicity, dermatological side effects, and abuse potential.
• Aminopyrine is a withdrawn drug. The year of withdrawal was 1999, countries it was withdrawn in include France, Thailand, reason(s) for withdrawal include risk of agranulocytosis and severe acne.
• Amobarbital is a withdrawn drug. The year of withdrawal was 1980, countries it was withdrawn in include Norway, reason(s) for withdrawal include Risk of overdose.
• Amoproxan is a withdrawn drug. The year of withdrawal was 1970, countries it was withdrawn in include France, reason(s) for withdrawal include Dermatologic and ophthalmic toxicity.
• Anagestone acetate is a withdrawn drug. The year of withdrawal was 1969, countries it was withdrawn in include Germany, reason(s) for withdrawal include Animal carcinogenicity.
• Antrafenine is a withdrawn drug. The year of withdrawal was 1984, countries it was withdrawn in include France, reason(s) for withdrawal include Unspecific experimental toxicity.
• Aprotinin (Trasylol) is a withdrawn drug. The year of withdrawal was 2008, countries it was withdrawn in include US, reason(s) for withdrawal include Increased risk of death.
• Ardepari n (Normiflo) is a withdrawn drug. The year of withdrawal was 2001, countries it was withdrawn in include US, reason(s) for withdrawal include Not for reasons of safety or efficacy.
• Astemizole (Hismanal) is a withdrawn drug. The year of withdrawal was 1999, countries it was withdrawn in include US, Malaysia, Multiple Nonspecified Markets, reason(s) for withdrawal include Fatal arrhythmia
• Azaribine is a withdrawn drug. The year of withdrawal was 1976, countries it was withdrawn in include US, reason(s) for withdrawal include Thromboembolism.
• Bendazac is a withdrawn drug. The year of withdrawal was 1993, countries it was withdrawn in include Spain, reason(s) for withdrawal include Hepatotoxicity.
• Benoxaprofen is a withdrawn drug. The year of withdrawal was 1982, countries it was withdrawn in include Germany, Spain, UK, US, reason(s) for withdrawal include Liver and kidney failure; gastrointestinal bleeding; ulcers.
• Benzarone is a withdrawn drug. The year of withdrawal was 1992, countries it was withdrawn in include Germany, reason(s) for withdrawal include Hepatitis.
• Benziodarone is a withdrawn drug. The year of withdrawal was 1964, countries it was withdrawn in include France, UK, reason(s) for withdrawal include Jaundice.
• Beta-ethoxy-lacetanilanide is a withdrawn drug. The year of withdrawal was 1986, countries it was withdrawn in include Germany, reason(s) for withdrawal include Renal toxicity, animal carcinogenicity.
• Bezitramide is a withdrawn drug. The year of withdrawal was 2004, countries it was withdrawn in include Netherlands, reason(s) for withdrawal include Risk of fatal overdose
• Bithionol is a withdrawn drug. The year of withdrawal was 1967, countries it was withdrawn in include US, reason(s) for withdrawal include Dermatologic toxicity.
• Bromfenac is a withdrawn drug. The year of withdrawal was 1998, countries it was withdrawn in include US, reason(s) for withdrawal include Severe hepatitis and liver failure (requiring transplantation).
• Brotizolam is a withdrawn drug. The year of withdrawal was 1989, countries it was withdrawn in include UK, reason(s) for withdrawal include Animal carcinogenicity.
• Bucetin is a withdrawn drug. The year of withdrawal was 1986, countries it was withdrawn in include Germany, reason(s) for withdrawal include Kidney damage
• Buformin is a withdrawn drug. The year of withdrawal was 1978, countries it was withdrawn in include Germany, reason(s) for withdrawal include Metabolic toxicity.
• Bunamiodyl is a withdrawn drug. The year of withdrawal was 1963, countries it was withdrawn in include Canada, UK, US, reason(s) for withdrawal include Nephropathy.
• Butamben (Efocaine)(Butoforme) is a withdrawn drug. The year of withdrawal was 1964, countries it was withdrawn in include US, reason(s) for withdrawal include Dermatologic toxicity; psychiatric Reactions.
• Canrenone is a withdrawn drug. The year of withdrawal was 1986, countries it was withdrawn in include Germany, reason(s) for withdrawal include Animal Carcinogenicity.
• Cerivastatin (Baycol, Lipobay) is a withdrawn drug. The year of withdrawal was 2001, countries it was withdrawn in include US, reason(s) for withdrawal include Risk of rhabdomyolysis
• Chlormadinone (Chlormenadione) is a withdrawn drug. The year of withdrawal was 1970, countries it was withdrawn in include UK, US, reason(s) for withdrawal include Animal Carcinogenicity.
• Chlormezanone (Trancopal) is a withdrawn drug. The year of withdrawal was 1996, countries it was withdrawn in include European Union, US, South Africa, Japan, reason(s) for withdrawal include Hepatotoxicity & Steven-Johnson Syndrome
• Chlorphentermine is a withdrawn drug. The year of withdrawal was 1969, countries it was withdrawn in include Germany, reason(s) for withdrawal include Cardiovascular Toxicity.
• Cianidanol is a withdrawn drug. The year of withdrawal was 1985, countries it was withdrawn in include France, Germany, Spain, Sweden, reason(s) for withdrawal include Hemolytic Anemia.
• Cinepazide is a withdrawn drug. The year of withdrawal was 1988, countries it was withdrawn in include Spain, reason(s) for withdrawal include Agranulocytosis.
• Cisapride (Propulsid) is a withdrawn drug. The year of withdrawal was 2000, countries it was withdrawn in include US, reason(s) for withdrawal include Risk of fatal cardiac arrhythmias
• Clioquinol is a withdrawn drug. The year of withdrawal was 1973, countries it was withdrawn in include France, Germany, UK, US, reason(s) for withdrawal include Neurotoxicity.
• Clobutinol is a withdrawn drug. The year of withdrawal was 2007, countries it was withdrawn in include Germany, reason(s) for withdrawal include Ventricular arrhythmia, QT-prolongation.
• Cloforex is a withdrawn drug. The year of withdrawal was 1969, countries it was withdrawn in include Germany, reason(s) for withdrawal include Cardiovascular toxicity.
• Clomacron is a withdrawn drug. The year of withdrawal was 1982, countries it was withdrawn in include UK, reason(s) for withdrawal include Hepatotoxicity.
• Clometacin is a withdrawn drug. The year of withdrawal was 1987, countries it was withdrawn in include France, reason(s) for withdrawal include Hepatotoxicity.
• Co-proxamol (Distalgesic) is a withdrawn drug. The year of withdrawal was 2004, countries it was withdrawn in include UK, reason(s) for withdrawal include Risk of overdose
• Cyclobarbital is a withdrawn drug. The year of withdrawal was 1980, countries it was withdrawn in include Norway, reason(s) for withdrawal include Risk of overdose
• Cyclofenil is a withdrawn drug. The year of withdrawal was 1987, countries it was withdrawn in include France, reason(s) for withdrawal include Hepatotoxicity.
• Dantron is a withdrawn drug. The year of withdrawal was 1963, countries it was withdrawn in include Canada, UK, US, reason(s) for withdrawal include Mutagenic. withdrawn from general use in UK but permitted in terminal patients
• Dexfenfluramine is a withdrawn drug. The year of withdrawal was 1997, countries it was withdrawn in include European Union, UK, US, reason(s) for withdrawal include Cardiotoxic
• Diacetoxydiphenolisatin is a withdrawn drug. The year of withdrawal was 1971, countries it was withdrawn in include Australia, reason(s) for withdrawal include Hepatotoxicity.
• Diethylstilbestrol is a withdrawn drug. The year of withdrawal was 1970s, countries it was withdrawn in include US, reason(s) for withdrawal include Carcinogen
• Difemerine is a withdrawn drug. The year of withdrawal was 1986, countries it was withdrawn in include Germany, reason(s) for withdrawal include Multi-Organ toxicities.
• Dihydrostreptomycin is a withdrawn drug. The year of withdrawal was 1970, countries it was withdrawn in include US, reason(s) for withdrawal include Neuropsychiatric reaction.
• Dilevalol is a withdrawn drug. The year of withdrawal was 1990, countries it was withdrawn in include UK, reason(s) for withdrawal include Hepatotoxicity.
• Dimazole (Diamthazole) is a withdrawn drug. The year of withdrawal was 1972, countries it was withdrawn in include France, US, reason(s) for withdrawal include Neuropsychiatric reaction.
• Dimethylamylamine (DMAA) is a withdrawn drug. The year of withdrawal was 1983, countries it was withdrawn in include US, reason(s) for withdrawal include Voluntarily withdrawn from market by Lily.:12 Reintroduced as a dietary supplement in 2006;:13 and in 2013 the FDA started work to ban it due to cardiovascular problems
• Dinoprostone is a withdrawn drug. The year of withdrawal was 1990, countries it was withdrawn in include UK, reason(s) for withdrawal include Uterine hypotonus, fetal distress.
• Dipyrone (Metamizole) is a withdrawn drug. The year of withdrawal was 1975, countries it was withdrawn in include UK, US, Others, reason(s) for withdrawal include Agranulocytosis, anaphylactic reactions.
• Dithiazanine iodide is a withdrawn drug. The year of withdrawal was 1964, countries it was withdrawn in include France, US, reason(s) for withdrawal include Cardiovascular and metabolic reaction.
• Dofetilide is a withdrawn drug. The year of withdrawal was 2004, countries it was withdrawn in include Germany, reason(s) for withdrawal include Drug interactions, prolonged QT.
• Ebrotidine is a withdrawn drug. The year of withdrawal was 1998, countries it was withdrawn in include Spain, reason(s) for withdrawal include Hepatotoxicity.
• Efalizumab (Raptiva) is a withdrawn drug. The year of withdrawal was 2009, countries it was withdrawn in include Germany, reason(s) for withdrawal include Withdrawn because of increased risk of progressive multifocal leukoencephalopathy
• Encainide is a withdrawn drug. The year of withdrawal was 1991, countries it was withdrawn in include UK, US, reason(s) for withdrawal include Ventricular arrhythmias.
• Etretinate is a withdrawn drug. The year of withdrawal was 1989, countries it was withdrawn in include France, reason(s) for withdrawal include Teratogen.
• Exifone is a withdrawn drug. The year of withdrawal was 1989, countries it was withdrawn in include France, reason(s) for withdrawal include Hepatotoxicity.
• Fenclofenac is a withdrawn drug. The year of withdrawal was 1984, countries it was withdrawn in include UK, reason(s) for withdrawal include Cutaneous reactions; animal carcinogenicity.
• Fenclozic acid is a withdrawn drug. The year of withdrawal was 1970, countries it was withdrawn in include UK, US, reason(s) for withdrawal include Hepatotoxicity.
• Fenfluramine is a withdrawn drug. The year of withdrawal was 1997, countries it was withdrawn in include European Union, UK, US, India, South Africa, others, reason(s) for withdrawal include Cardiac valvular disease, pulmonary hypertension, cardiac fibrosis; re-approved in June 2020 for the treatment of seizures associated with Dravet syndrome, under FDA orphan drug rules.
• Fenoterol is a withdrawn drug. The year of withdrawal was 1990, countries it was withdrawn in include New Zealand, reason(s) for withdrawal include Asthma mortality.
• Feprazone is a withdrawn drug. The year of withdrawal was 1984, countries it was withdrawn in include Germany, UK, reason(s) for withdrawal include Cutaneous reaction, multiorgan toxicity.
• Fipexide is a withdrawn drug. The year of withdrawal was 1991, countries it was withdrawn in include France, reason(s) for withdrawal include Hepatotoxicity.
• Flosequinan (Manoplax) is a withdrawn drug. The year of withdrawal was 1993, countries it was withdrawn in include UK, US, reason(s) for withdrawal include Increased mortality at higher doses; increased hospitalizations.
• Flunitrazepam is a withdrawn drug. The year of withdrawal was 1991, countries it was withdrawn in include France, reason(s) for withdrawal include Abuse.
• Flupirtine is a withdrawn drug. The year of withdrawal was 2018, countries it was withdrawn in include European Union, reason(s) for withdrawal include Liver toxicity.
• Gatifloxacin is a withdrawn drug. The year of withdrawal was 2006, countries it was withdrawn in include US, reason(s) for withdrawal include Increased risk of dysglycemia.
• Glafenine is a withdrawn drug. The year of withdrawal was 1984, countries it was withdrawn in include France, Germany, reason(s) for withdrawal include Anaphylaxis.
• Grepafloxacin (Raxar) is a withdrawn drug. The year of withdrawal was 1999, countries it was withdrawn in include Withdrawn Germany, UK, US others, reason(s) for withdrawal include Cardiac repolarization; QT interval prolongation.
• Ibufenac is a withdrawn drug. The year of withdrawal was 1968, countries it was withdrawn in include UK, reason(s) for withdrawal include Hepatotoxicity, jaundice.
• Indalpine is a withdrawn drug. The year of withdrawal was 1985, countries it was withdrawn in include France, reason(s) for withdrawal include Agranulocytosis.
• Indoprofen is a withdrawn drug. The year of withdrawal was 1983, countries it was withdrawn in include Germany, Spain, UK, reason(s) for withdrawal include Animal carcinogenicity, gastrointestinal toxicity.
• Iodinated casein strophantin is a withdrawn drug. The year of withdrawal was 1964, countries it was withdrawn in include US, reason(s) for withdrawal include Metabolic reaction.
• Iproniazid is a withdrawn drug. The year of withdrawal was 1964, countries it was withdrawn in include Canada, reason(s) for withdrawal include Interactions with food products containing tyrosine.
• Isoxicam is a withdrawn drug. The year of withdrawal was 1983, countries it was withdrawn in include France, Germany, Spain, others, reason(s) for withdrawal include Stevens johnson syndrome.
• Ketorolac is a withdrawn drug. The year of withdrawal was 1993, countries it was withdrawn in
• L-tryptophan is a withdrawn drug. The year of withdrawal was 1989, countries it was withdrawn in include Germany, UK, reason(s) for withdrawal include Eosinophilic myalgia syndrome. Still sold in the US
• Levamisole (Ergamisol) is a withdrawn drug. The year of withdrawal was 1999, countries it was withdrawn in include US, reason(s) for withdrawal include Still used as veterinary drug and as a human antihelminthic in many markets; listed on the WHO List of Essential Medicines. In humans, it was used to treat melanoma before it was withdrawn for agranulocytosis.
• Levomethadyl acetate is a withdrawn drug. The year of withdrawal was 2003, countries it was withdrawn in include US, reason(s) for withdrawal include Cardiac arrhythmias and cardiac arrest.
• Lorcaserin (Belviq) is a withdrawn drug. The year of withdrawal was 2020, countries it was withdrawn in include US, reason(s) for withdrawal include Increased risk of cancer.
• Lumiracoxib (Prexige) is a withdrawn drug. The year of withdrawal was 2007–2008, countries it was withdrawn in include Worldwide, reason(s) for withdrawal include Liver damage
• Lysergic acid diethylamide (LSD) is a withdrawn drug. The year of withdrawal was 1950s–1960s, reason(s) for withdrawal include , countries it was withdrawn in include Marketed as a psychiatric drug; withdrawn after it became widely used recreationally. Now illegal in most of the world.
• Mebanazine is a withdrawn drug. The year of withdrawal was 1975, countries it was withdrawn in include UK, reason(s) for withdrawal include Hepatotoxicity, drug intereaction.
• Methandrostenolone is a withdrawn drug. The year of withdrawal was 1982, countries it was withdrawn in include France, Germany, UK, US, others, reason(s) for withdrawal include Off-label abuse.
• Methapyrilene is a withdrawn drug. The year of withdrawal was 1979, countries it was withdrawn in include Germany, UK, US, reason(s) for withdrawal include Animal carcinogenicity.
• Methaqualone is a withdrawn drug. The year of withdrawal was 1984, countries it was withdrawn in include South Africa (1971), India (1984), United Nations (1971–1988), reason(s) for withdrawal include Withdrawn because of risk of addiction and overdose
• Metipranolol is a withdrawn drug. The year of withdrawal was 1990, countries it was withdrawn in include UK, others, reason(s) for withdrawal include Uveitis.
• Metofoline is a withdrawn drug. The year of withdrawal was 1965, countries it was withdrawn in include US, reason(s) for withdrawal include Unspecific experimental toxicity.
• Mibefradil is a withdrawn drug. The year of withdrawal was 1998, countries it was withdrawn in include European Union, Malaysia, US, others, reason(s) for withdrawal include Fatal arrhythmia, drug interactions.
• Minaprine is a withdrawn drug. The year of withdrawal was 1996, countries it was withdrawn in include France, reason(s) for withdrawal include Convulsions.
• Moxisylyte is a withdrawn drug. The year of withdrawal was 1993, countries it was withdrawn in include France, reason(s) for withdrawal include Necrotic hepatitis.
• Muzolimine is a withdrawn drug. The year of withdrawal was 1987, countries it was withdrawn in include France, Germany, European Union, reason(s) for withdrawal include Polyneuropathy.
• Natalizumab (Tysabri) is a withdrawn drug. The year of withdrawal was 2005–2006, countries it was withdrawn in include US, reason(s) for withdrawal include Voluntarily withdrawn from US market because of risk of Progressive multifocal leukoencephalopathy (PML). Returned to market July, 2006.
• Nefazodone is a withdrawn drug. The year of withdrawal was 2007, countries it was withdrawn in include US, Canada, others, reason(s) for withdrawal include Branded version withdrawn by originator in several countries in 2007 for hepatotoxicity. Generic versions available.
• Nialamide is a withdrawn drug. The year of withdrawal was 1974, countries it was withdrawn in include UK, US, reason(s) for withdrawal include Hepatotoxicity, drug intereaction.
• Nikethamide is a withdrawn drug. The year of withdrawal was 1988, countries it was withdrawn in include multiple markets, reason(s) for withdrawal include CNS Stimulation.
• Nitrefazole is a withdrawn drug. The year of withdrawal was 1984, countries it was withdrawn in include Germany, reason(s) for withdrawal include Hepatic and hematologic toxicity.
• Nomifensine is a withdrawn drug. The year of withdrawal was 1981–1986, countries it was withdrawn in include France, Germany, Spain, UK, US, others, reason(s) for withdrawal include Hemolytic Anemia, hepatotoxicity, serious hypersensitive reactions.
• Oxeladin is a withdrawn drug. The year of withdrawal was 1976, countries it was withdrawn in include Canada, UK, US (1976), reason(s) for withdrawal include Carcinogen.
• Oxyphenbutazone is a withdrawn drug. The year of withdrawal was 1984–1985, countries it was withdrawn in include UK, US, Germany, France, Canada, reason(s) for withdrawal include Bone marrow suppression, Stevens–Johnson syndrome.
• Oxyphenisatin (Phenisatin), reason(s) for withdrawal include Australia, France, Germany, UK, US, reason(s) for withdrawal include Hepatotoxicity.
• Ozogamicin is a withdrawn drug. The year of withdrawal was 2010, countries it was withdrawn in include US, reason(s) for withdrawal include No improvement in clinical benefit; risk for death; veno-occlusive disease.
• Pemoline (Cylert) is a withdrawn drug. The year of withdrawal was 1997, countries it was withdrawn in include Canada, UK, reason(s) for withdrawal include Withdrawn from US in 2005. Hepatotoxicity Reason:hepatotoxicity.
• Pentobarbital is a withdrawn drug. The year of withdrawal was 1980, countries it was withdrawn in include Norway, reason(s) for withdrawal include Risk of fatal overdose
• Pentylenetetrazol is a withdrawn drug. The year of withdrawal was 1982, countries it was withdrawn in include US, reason(s) for withdrawal include Withdrawn for inability to produce effective convulsive therapy, and for causing seizures.
• Pergolide (Permax) is a withdrawn drug. The year of withdrawal was 2007, countries it was withdrawn in include US, reason(s) for withdrawal include Risk for heart valve damage.
• Perhexiline is a withdrawn drug. The year of withdrawal was 1985, countries it was withdrawn in include UK, Spain, reason(s) for withdrawal include Neurologic and hepatic toxicity.
• Phenacetin is a withdrawn drug. The year of withdrawal was 1975, countries it was withdrawn in include Canada, reason(s) for withdrawal include An ingredient in "A.P.C." tablet; withdrawn because of risk of cancer and kidney disease Germany Denmark, UK, US, others Reason: nephropathy.
• Phenformin and Buformin is a withdrawn drug. The year of withdrawal was 1977, countries it was withdrawn in include France, Germany US, reason(s) for withdrawal include Severe lactic acidosis
• Phenolphthalein is a withdrawn drug. The year of withdrawal was 1997, countries it was withdrawn in include US, reason(s) for withdrawal include Possible carcinogen.
• Phenoxypropazine is a withdrawn drug. The year of withdrawal was 1966, countries it was withdrawn in include UK, reason(s) for withdrawal include Hepatotoxicity, drug interaction.
• Phenylbutazone is a withdrawn drug. The year of withdrawal was 1985, countries it was withdrawn in include Germany, reason(s) for withdrawal include Off-label abuse, hematologic toxicity.
• Phenylpropanolamine (Propagest, Dexatrim) is a withdrawn drug. The year of withdrawal was 2000, countries it was withdrawn in include Canada, US, reason(s) for withdrawal include Hemorrhagic stroke.
• Pifoxime (Pixifenide) is a withdrawn drug. The year of withdrawal was 1976, countries it was withdrawn in include France, reason(s) for withdrawal include Neuropsychiatric reaction.
• Pirprofen is a withdrawn drug. The year of withdrawal was 1990, countries it was withdrawn in include France, Germany, Spain, reason(s) for withdrawal include Liver toxicity.:223
• Prenylamine is a withdrawn drug. The year of withdrawal was 1988, countries it was withdrawn in include Canada, France, Germany, UK, US, others, reason(s) for withdrawal include Cardiac arrythmia and death.
• Proglumide is a withdrawn drug. The year of withdrawal was 1989, countries it was withdrawn in include Germany, reason(s) for withdrawal include Respiratory reaction.
• Pronethalol is a withdrawn drug. The year of withdrawal was 1965, countries it was withdrawn in include UK, reason(s) for withdrawal include Animal carcinogenicity.
• Propanidid is a withdrawn drug. The year of withdrawal was 1983, countries it was withdrawn in include UK, reason(s) for withdrawal include Allergy.
• Propoxyphene (Darvocet/Darvon) is a withdrawn drug. The year of withdrawal was 2010, countries it was withdrawn in include Worldwide, reason(s) for withdrawal include Increased risk of heart attacks and stroke.
• Proxibarbal is a withdrawn drug. The year of withdrawal was 1998, countries it was withdrawn in include Spain, France, Italy, Portugal, Turkey, reason(s) for withdrawal include Immunoallergic, thrombocytopenia.
• Pyrovalerone is a withdrawn drug. The year of withdrawal was 1979, countries it was withdrawn in include France, reason(s) for withdrawal include Abuse.
• Rapacuronium (Raplon) is a withdrawn drug. The year of withdrawal was 2001, countries it was withdrawn in include US, multiple markets, reason(s) for withdrawal include Withdrawn in many countries because of risk of fatal bronchospasm
• Remoxipride is a withdrawn drug. The year of withdrawal was 1993, countries it was withdrawn in include UK, others, reason(s) for withdrawal include Aplastic anemia.
• Rimonabant (Acomplia) is a withdrawn drug. The year of withdrawal was 2008, countries it was withdrawn in include Worldwide, reason(s) for withdrawal include Risk of severe depression and suicide
• Rofecoxib (Vioxx) is a withdrawn drug. The year of withdrawal was 2004, countries it was withdrawn in include Worldwide, reason(s) for withdrawal include Withdrawn by Merck & Co. Risk of myocardial infarction and stroke
• Rosiglitazone (Avandia) is a withdrawn drug. The year of withdrawal was 2010, countries it was withdrawn in include Europe, reason(s) for withdrawal include Risk of heart attacks and death. This drug continues to be available in the US
• Secobarbital is a withdrawn drug. The reason(s) for withdrawal include France, Norway, others., reason(s) for withdrawal include Risk of overdose
• Sertindole is a withdrawn drug. The year of withdrawal was 1998, countries it was withdrawn in include European Union, reason(s) for withdrawal include Arrhythmia and sudden cardiac death
• Sibutramine (Reductil/Meridia) is a withdrawn drug. The year of withdrawal was 2010, countries it was withdrawn in include Australia, Canada, China, the European Union (EU), Hong Kong, India, Mexico, New Zealand, the Philippines, Thailand, the United Kingdom, and the United States, reason(s) for withdrawal include Increased risk of heart attack and stroke.
• Sitaxentan is a withdrawn drug. The year of withdrawal was 2010, countries it was withdrawn in include Germany, reason(s) for withdrawal include Hepatotoxicity.
• Sorivudine is a withdrawn drug. The year of withdrawal was 1993, countries it was withdrawn in include Japan, reason(s) for withdrawal include Drug interaction and deaths.
• Sparfloxacin is a withdrawn drug. The year of withdrawal was 2001, countries it was withdrawn in include US, reason(s) for withdrawal include QT prolongation and phototoxicity.
• Sulfacarbamide is a withdrawn drug. The year of withdrawal was 1988, countries it was withdrawn in include Germany, reason(s) for withdrawal include Dermatologic, hematologic and hepatic reactions.
• Sulfamethoxydiazine is a withdrawn drug. The year of withdrawal was 1988, countries it was withdrawn in include Germany, reason(s) for withdrawal include Unknown.
• Sulfamethoxypyridazine is a withdrawn drug. The year of withdrawal was 1986, countries it was withdrawn in include UK, reason(s) for withdrawal include Dermatologic and hematologic reactions.
• Suloctidil is a withdrawn drug. The year of withdrawal was 1985, countries it was withdrawn in include Germany, France, Spain, reason(s) for withdrawal include Hepatotoxicity.
• Suprofen is a withdrawn drug. The year of withdrawal was 1986–1987, countries it was withdrawn in include UK, Spain, US, reason(s) for withdrawal include Kidney damage.
• Tegaserod (Zelnorm) is a withdrawn drug. The year of withdrawal was 2007, countries it was withdrawn in include US, reason(s) for withdrawal include Risk for heart attack, stroke, and unstable angina. Was available through a restricted access program until April 2008; returned to market in 2019.
• Temafloxacin is a withdrawn drug. The year of withdrawal was 1992, countries it was withdrawn in include Germany, UK, US, others, reason(s) for withdrawal include Low blood sugar; hemolytic anemia; kidney, liver dysfunction; allergic reactions
• Temafloxacin is a withdrawn drug. The year of withdrawal was 1992, countries it was withdrawn in include US, reason(s) for withdrawal include Allergic reactions and cases of hemolytic anemia, leading to three patient deaths.
• Temazepam (Restoril, Euhypnos, Normison, Remestan, Tenox, Norkotral) is a withdrawn drug. The year of withdrawal was 1999, countries it was withdrawn in include Sweden, Norway, reason(s) for withdrawal include Diversion, abuse, and a relatively high rate of overdose deaths in comparison to other drugs of its group. This drug continues to be available in most of the world including the US, but under strict controls.
• Terfenadine (Seldane, Triludan) is a withdrawn drug. The year of withdrawal was 1997–1998, countries it was withdrawn in include France, South Africa, Oman, others, US, reason(s) for withdrawal include Prolonged QT interval; ventricular tachycardia
• Terodiline (Micturin) is a withdrawn drug. The year of withdrawal was 1991, countries it was withdrawn in include Germany, UK, Spain, others, reason(s) for withdrawal include Prolonged QT interval, ventricular tachycardia and arrhythmia.
• Tetrazepam is a withdrawn drug. The year of withdrawal was 2013, countries it was withdrawn in include European Union, reason(s) for withdrawal include Serious cutaneous reactions.
• Thalidomide is a withdrawn drug. The year of withdrawal was 1961, countries it was withdrawn in include Germany, reason(s) for withdrawal include Withdrawn because of risk of teratogenicity; returned to market for use in leprosy and multiple myeloma under FDA orphan drug rules
• Thenalidine is a withdrawn drug. The year of withdrawal was 1963, countries it was withdrawn in include Canada, UK, US, reason(s) for withdrawal include Neutropenia
• Thiobutabarbitone is a withdrawn drug. The year of withdrawal was 1993, countries it was withdrawn in include Germany, reason(s) for withdrawal include Kidney injury.
• Thioridazine (Melleril) is a withdrawn drug. The year of withdrawal was 2005, countries it was withdrawn in include Germany, UK, reason(s) for withdrawal include Withdrawn worldwide due to severe cardiac arrhythmias
• Ticrynafen (Tienilic acid) is a withdrawn drug. The year of withdrawal was 1980, countries it was withdrawn in include Germany, France, UK, US others, reason(s) for withdrawal include Liver toxicity and death.
• Tolcapone (Tasmar) is a withdrawn drug. The year of withdrawal was 1998, countries it was withdrawn in include European Union, Canada, Australia, reason(s) for withdrawal include Hepatotoxicity
• Tolrestat (Alredase) is a withdrawn drug. The year of withdrawal was 1996, countries it was withdrawn in include Argentina, Canada, Italy, others, reason(s) for withdrawal include Severe hepatotoxicity
• Triacetyldiphenolisatin is a withdrawn drug. The year of withdrawal was 1971, countries it was withdrawn in include Australia, reason(s) for withdrawal include Hepatotoxicity.
• Triazolam is a withdrawn drug. The year of withdrawal was 1991, countries it was withdrawn in include France, Netherlands, Finland, Argentina, UK others, reason(s) for withdrawal include Psychiatric adverse drug reactions, amnesia.
• Triparanol is a withdrawn drug. The year of withdrawal was 1962, countries it was withdrawn in include France, US, reason(s) for withdrawal include Cataracts, alopecia, ichthyosis.
• Troglitazone (Rezulin) is a withdrawn drug. The year of withdrawal was 2000, countries it was withdrawn in include US, Germany, reason(s) for withdrawal include Hepatotoxicity
• Trovafloxacin (Trovan) is a withdrawn drug. The year of withdrawal was 1999–2001, countries it was withdrawn in include European Union, US, reason(s) for withdrawal include Withdrawn because of risk of liver failure
• Valdecoxib (Bextra) is a withdrawn drug. The year of withdrawal was 2004, countries it was withdrawn in include US, reason(s) for withdrawal include Risk of heart attack and stroke.
• Vincamine is a withdrawn drug. The year of withdrawal was 1987, countries it was withdrawn in include Germany, reason(s) for withdrawal include Hematologic toxicity.
• Xenazoic acid is a withdrawn drug. The year of withdrawal was 1965, countries it was withdrawn in include France, reason(s) for withdrawal include Hepatotoxicity.
• Ximelagatran (Exanta) is a withdrawn drug. The year of withdrawal was 2006, countries it was withdrawn in include Germany, reason(s) for withdrawal include Hepatotoxicity.
• Zimelidine is a withdrawn drug. The year of withdrawal was 1983, countries it was withdrawn in include Worldwide, reason(s) for withdrawal include Risk of Guillain–Barré syndrome, hypersensitivity reaction, hepatotoxicity banned worldwide.
• Zomepirac is a withdrawn drug. The year of withdrawal was 1983, countries it was withdrawn in include UK, Germany, Spain, US, reason(s) for withdrawal include Anaphylactic reactions and non-fatal allergic reactions, kidney failure.
• rhesus rotavirus vaccine-tetravalent (RotaShield) is a withdrawn drug. The year of withdrawal was 1999, countries it was withdrawn in include US, reason(s) for withdrawal include Withdrawn due to risk of intussusception

include France, Germany, others, reason(s) for withdrawal include Hemorrhage, Kidney Failure.

Also see

• Abandoned drugs
• Investigational drugs

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