Sulfamethoxypyridazine

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Sulfamethoxypyridazine is a sulfonamide antibiotic used in the treatment of various bacterial infections. It is a long-acting sulfonamide that is often used in veterinary medicine, but can also be used in humans.

History[edit | edit source]

Sulfamethoxypyridazine was first synthesized in the 1940s as part of a larger effort to develop effective antibacterial agents. It is part of the sulfonamide class of antibiotics, which were among the first systemic antibacterial agents to be used in medicine.

Mechanism of Action[edit | edit source]

Sulfamethoxypyridazine works by inhibiting the enzyme dihydropteroate synthase, which is necessary for the synthesis of folic acid. Bacteria need folic acid to survive and reproduce, so by inhibiting its production, sulfamethoxypyridazine effectively kills the bacteria.

Uses[edit | edit source]

Sulfamethoxypyridazine is used to treat a variety of bacterial infections, including urinary tract infections, respiratory tract infections, and skin infections. It is also used in veterinary medicine to treat infections in animals.

Side Effects[edit | edit source]

Like all medications, sulfamethoxypyridazine can cause side effects. These can include nausea, vomiting, diarrhea, and allergic reactions. In rare cases, it can cause serious side effects like anemia, liver damage, and kidney damage.

See Also[edit | edit source]

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Contributors: Prab R. Tumpati, MD