Carindacillin
Carindacillin, recognized by the International Nonproprietary Name (INN) and known in the U.S. as Carbenicillin indanyl (USAN), is a penicillin-based antibiotic. It functions as a prodrug of carbenicillin and belongs to the broader class of Beta-lactam antibiotics. The renowned pharmaceutical company, Pfizer, markets Carindacillin under the trademark Geocillin.
Classification[edit | edit source]
- Type: Penicillin antibiotic
- Prodrug of: Carbenicillin
Pharmacology and Usage[edit | edit source]
Mechanism of Action[edit | edit source]
As a prodrug, Carindacillin is metabolized in the body to produce its active form, carbenicillin. This active antibiotic then targets bacterial cell wall synthesis, disrupting the formation of peptidoglycan chains essential for bacterial cell wall strength and rigidity.
Administration[edit | edit source]
Carindacillin is typically administered orally in the form of its sodium salt. This enhances its solubility and ensures effective absorption within the gastrointestinal tract.
Commercial Information[edit | edit source]
- Brand Name: Geocillin
- Manufacturer: Pfizer
- Marketing Regions: Carindacillin, under the Geocillin brand, is available in various regions, with specific approval and marketing details varying by jurisdiction.
Safety and Precautions[edit | edit source]
Like all antibiotics, it's crucial to complete the full course of Carindacillin, even if symptoms improve before completion. This practice helps prevent antibiotic resistance. Patients with a known allergy to penicillins or other beta-lactam antibiotics should avoid Carindacillin or use it under close medical supervision.
Conclusion[edit | edit source]
Carindacillin stands as a significant member of the penicillin antibiotic class, offering an oral route of administration for conditions where carbenicillin's action is desired. Its development and marketing by Pfizer under the Geocillin brand has expanded the range of options available to healthcare professionals in the fight against bacterial infections.
See Also[edit | edit source]
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