Pirlimycin
Pirlimycin is an antibiotic used in veterinary medicine to treat mastitis in dairy cattle. It is a member of the lincosamide class of antibiotics and works by inhibiting protein synthesis in susceptible bacteria.
Chemistry[edit | edit source]
Pirlimycin is a semi-synthetic antibiotic, derived from lincomycin. It is a white to off-white crystalline powder that is soluble in water. The chemical name for pirlimycin is N-[[2-[[2-(1-methyl-2-pyrrolidinyl)ethyl]thio]ethyl]-6,11-dihydro-4-(1-methyl-3,3-diphenyl-propyl)-1H-pyrrolo[2,1-c][1,4]benzodiazepin-1-one.
Pharmacology[edit | edit source]
Pirlimycin is bacteriostatic, meaning it inhibits the growth of bacteria rather than killing them directly. It works by binding to the 50S subunit of the bacterial ribosome, thereby inhibiting protein synthesis. Pirlimycin is effective against a range of Gram-positive bacteria, including Staphylococcus aureus and Streptococcus agalactiae, which are common causes of bovine mastitis.
Usage[edit | edit source]
Pirlimycin is administered intramammary, meaning it is injected directly into the udder. It is used to treat mastitis in lactating dairy cows, and is particularly effective against infections caused by Staphylococcus aureus and Streptococcus agalactiae. Treatment typically involves a single dose, although severe infections may require additional doses.
Safety[edit | edit source]
As with all antibiotics, overuse of pirlimycin can lead to the development of antibiotic resistance. Therefore, it should be used only when necessary and under the supervision of a veterinarian. Milk from cows treated with pirlimycin should not be used for human consumption until a specified withdrawal period has passed to ensure that residues of the drug have been eliminated.
See also[edit | edit source]
| This article is a stub. You can help WikiMD by registering to expand it. |
This veterinary medicine related article is a stub. You can help WikiMD by expanding it.
Search WikiMD
Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro / Zepbound) available.
Advertise on WikiMD
|
WikiMD's Wellness Encyclopedia |
| Let Food Be Thy Medicine Medicine Thy Food - Hippocrates |
Translate this page: - East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
தமிழ்,
తెలుగు,
Urdu,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
বাংলা
European
español,
Deutsch,
français,
Greek,
português do Brasil,
polski,
română,
русский,
Nederlands,
norsk,
svenska,
suomi,
Italian
Middle Eastern & African
عربى,
Turkish,
Persian,
Hebrew,
Afrikaans,
isiZulu,
Kiswahili,
Other
Bulgarian,
Hungarian,
Czech,
Swedish,
മലയാളം,
मराठी,
ਪੰਜਾਬੀ,
ગુજરાતી,
Portuguese,
Ukrainian
Medical Disclaimer: WikiMD is not a substitute for professional medical advice. The information on WikiMD is provided as an information resource only, may be incorrect, outdated or misleading, and is not to be used or relied on for any diagnostic or treatment purposes. Please consult your health care provider before making any healthcare decisions or for guidance about a specific medical condition. WikiMD expressly disclaims responsibility, and shall have no liability, for any damages, loss, injury, or liability whatsoever suffered as a result of your reliance on the information contained in this site. By visiting this site you agree to the foregoing terms and conditions, which may from time to time be changed or supplemented by WikiMD. If you do not agree to the foregoing terms and conditions, you should not enter or use this site. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates Wikipedia, licensed under CC BY SA or similar.
Contributors: Prab R. Tumpati, MD
