Ciprofol

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Ciprofol


Ciprofloxacin is a broad-spectrum antibiotic of the fluoroquinolone class. It is commonly used to treat a variety of bacterial infections. Ciprofloxacin was introduced in 1987 and is manufactured by Bayer.

History[edit | edit source]

Ciprofloxacin was first patented in 1983 by Bayer A.G. and it became available in the market in 1987. It was the second fluoroquinolone brought to the market by Bayer, following norfloxacin.

Medical Uses[edit | edit source]

Ciprofloxacin is used to treat a wide variety of infections, including infections of bones and joints, endocarditis, gastroenteritis, malignant otitis externa, respiratory tract infections, cellulitis, urinary tract infections, prostatitis, anthrax, and chancroid.

Side Effects[edit | edit source]

Common side effects of ciprofloxacin include nausea, vomiting, diarrhea and rash. It may also increase the risk of tendinitis and tendon rupture in older patients.

Mechanism of Action[edit | edit source]

Ciprofloxacin is a broad-spectrum antibiotic that inhibits the A subunits of DNA gyrase, preventing DNA supercoiling and DNA synthesis.

Resistance[edit | edit source]

Bacterial resistance to ciprofloxacin occurs due to overuse, especially in healthcare settings.

See Also[edit | edit source]

References[edit | edit source]

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Contributors: Prab R. Tumpati, MD