Behcet's disease

Behcet's disease is a rare, chronic inflammatory disorder.

Behcets disease

Cause

The cause of Behcet's disease is unknown, but current research suggests that both genetic and  environmental factors play a role.  

Onset

Behcet's disease generally begins when individuals are in their 20s or 30s, although it can happen at any age. It tends to occur more often in men than in women.

Symptoms

Symptoms of Behcet's disease include recurrent ulcers in the mouth (resembling canker sores) and on the genitals, and eye inflammation.

Skin lesions

The disorder may also cause various types of skin lesions, arthritis, bowel inflammation, meningitis (inflammation of the membranes of the brain and spinal cord), and cranial nerve palsies.

Behcet fundus

Systemic involvement

Behcet's is a multi-system disease; it may involve all organs and affect the central nervous system, causing memory loss and impaired speech, balance, and movement.

Complications

The effects of the disease may include blindness, stroke, swelling of the spinal cord, and intestinal complications.

Geographic distribution

The disease is common in the Middle East, particularly in Turkey, and in Far Eastern nations such as Japan and Korean, but is less common in the United States.