Fordyce spots

From WikiMD's Wellness Encyclopedia

(Redirected from Fordyce's disease)

Fordyce spots, also known as Fordyce granules, are ectopic sebaceous glands that are visible to the naked eye. They are a natural occurrence and present in a majority of individuals. Their presentation, although harmless, can sometimes cause cosmetic concerns or fear of sexually transmitted diseases.

Appearance and Location[edit | edit source]

Fordyce spots are characterized by small, painless, raised bumps that are pale, red or white in color. The spots typically measure between 1 to 3 mm in diameter. They most commonly appear on the genitals, including the scrotum and shaft of the penis in males and the labia in females. However, they can also be found on the face, specifically on the inner surface of the lips (retromolar mucosa) and along the vermilion border.

Pathophysiology[edit | edit source]

Close-up of lips with fordyce spots
Fordyce spots on lips

Sebaceous glands are typically associated with hair follicles, but in the case of Fordyce spots, these glands are found in a free-standing state directly in the mucosal surfaces. Despite their unusual location, they continue to secrete sebum, an oily substance that lubricates the skin and protects it from bacterial invasion.

Clinical Significance[edit | edit source]

Fordyce spots are not associated with any disease or illness, nor are they infectious. They represent a normal anatomical variant rather than a pathological condition. As such, no treatment is required unless individuals are concerned about their appearance.

Differential Diagnosis[edit | edit source]

Due to their appearance and location, individuals with Fordyce spots may initially fear that they have a sexually transmitted disease. However, a proper diagnosis from a dermatologist can quickly dispel such worries. It is important for healthcare providers to reassure patients about the benign nature of Fordyce spots to alleviate their anxiety.

Management and Treatment[edit | edit source]

While Fordyce spots do not require treatment, options are available for those who have cosmetic concerns. These include topical retinoids, oral isotretinoin, laser treatments, and surgical excision, among others. However, these treatments can have side effects and may not completely remove the spots or prevent them from reappearing.

Fordyce spots Resources
Wikipedia
WikiMD
Navigation: Wellness - Encyclopedia - Health topics - Disease Index‏‎ - Drugs - World Directory - Gray's Anatomy - Keto diet - Recipes

Search WikiMD

Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro / Zepbound) available.
Advertise on WikiMD

WikiMD's Wellness Encyclopedia

Let Food Be Thy Medicine
Medicine Thy Food - Hippocrates

Medical Disclaimer: WikiMD is not a substitute for professional medical advice. The information on WikiMD is provided as an information resource only, may be incorrect, outdated or misleading, and is not to be used or relied on for any diagnostic or treatment purposes. Please consult your health care provider before making any healthcare decisions or for guidance about a specific medical condition. WikiMD expressly disclaims responsibility, and shall have no liability, for any damages, loss, injury, or liability whatsoever suffered as a result of your reliance on the information contained in this site. By visiting this site you agree to the foregoing terms and conditions, which may from time to time be changed or supplemented by WikiMD. If you do not agree to the foregoing terms and conditions, you should not enter or use this site. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates Wikipedia, licensed under CC BY SA or similar.

Contributors: Prab R. Tumpati, MD