O-1861

O-1861 is a synthetic compound that acts as a potent and selective agonist for the cannabinoid receptors. It is primarily used in scientific research to study the endocannabinoid system and its role in various physiological processes.

Chemical Structure and Properties

O-1861 is a derivative of the cannabinoid class of compounds, which are known for their interaction with the cannabinoid receptors, CB1 and CB2. The chemical structure of O-1861 includes a core structure that is similar to other cannabinoids, with specific modifications that enhance its selectivity and potency.

Pharmacology

O-1861 exhibits high affinity for the CB1 receptor, which is predominantly found in the central nervous system. This receptor is involved in the modulation of neurotransmitter release, and its activation by O-1861 can lead to various effects such as analgesia, appetite stimulation, and mood alteration.

The compound also shows activity at the CB2 receptor, which is primarily located in the immune system. Activation of CB2 receptors by O-1861 can influence immune responses and has potential implications in the treatment of inflammatory conditions.

Research Applications

O-1861 is utilized in preclinical studies to explore the therapeutic potential of cannabinoid receptor modulation. It is used to investigate the effects of CB1 and CB2 receptor activation in models of pain, inflammation, and neurodegenerative diseases.

Safety and Toxicology

As with many research chemicals, the safety profile of O-1861 is not fully established. Studies in animal models are ongoing to determine its potential toxicological effects and therapeutic window.

Legal Status

The legal status of O-1861 varies by country. In some jurisdictions, it may be classified as a controlled substance due to its activity at cannabinoid receptors, while in others it may be available for research purposes.

Also see

• Cannabinoid receptor
• Endocannabinoid system
• CB1 receptor
• CB2 receptor
• Synthetic cannabinoids