PSB-36
PSB-36 is a chemical compound that acts as a selective antagonist for the adenosine A1 receptor. It is primarily used in scientific research to study the physiological and pharmacological roles of adenosine receptors in the body.
Pharmacology[edit | edit source]
PSB-36 is known for its high affinity and selectivity towards the adenosine A1 receptor, which is one of the four known adenosine receptor subtypes, the others being adenosine A2A receptor, adenosine A2B receptor, and adenosine A3 receptor. The adenosine A1 receptor is involved in various physiological processes, including cardiac function, renal blood flow, and neurotransmission.
By blocking the adenosine A1 receptor, PSB-36 can help elucidate the role of this receptor in different biological systems. It is often used in in vitro and in vivo studies to investigate the effects of adenosine receptor modulation.
Chemical Properties[edit | edit source]
PSB-36 is a synthetic compound with a specific chemical structure that allows it to bind selectively to the adenosine A1 receptor. The molecular formula of PSB-36 is CxHyNzOw, and it has a molecular weight of approximately XYZ g/mol. The compound is typically synthesized in a laboratory setting and is available in various forms for research purposes.
Applications in Research[edit | edit source]
PSB-36 is widely used in pharmacological research to:
- Study the role of adenosine A1 receptors in the central nervous system and their involvement in neurological disorders such as epilepsy and Parkinson's disease.
- Investigate the effects of adenosine A1 receptor antagonism on cardiovascular function, including heart rate and blood pressure regulation.
- Explore the potential therapeutic applications of adenosine receptor antagonists in treating conditions like chronic pain and inflammation.
Safety and Handling[edit | edit source]
As with many research chemicals, PSB-36 should be handled with care. Appropriate safety measures, including the use of personal protective equipment (PPE) and working in a controlled laboratory environment, are recommended to prevent exposure and ensure safe handling.
Also see[edit | edit source]
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