Thyrotropin alfa

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Thyrotropin alfa (also known as thyroid stimulating hormone, TSH, or thyrotropin) is a biopharmaceutical medication that is used to diagnose thyroid disorders and to monitor the treatment of thyroid cancer. It is a recombinant form of the human thyroid-stimulating hormone.

Medical uses[edit | edit source]

Thyrotropin alfa is used in the diagnosis of hypothyroidism, hyperthyroidism, and certain types of thyroid cancer. It is also used to monitor the treatment of thyroid cancer.

Mechanism of action[edit | edit source]

Thyrotropin alfa works by stimulating the thyroid gland to produce more thyroid hormone. This helps to regulate the body's metabolism and energy levels.

Side effects[edit | edit source]

Common side effects of thyrotropin alfa include nausea, headache, fatigue, and dizziness. In rare cases, it can cause serious side effects such as allergic reactions, heart problems, and stroke.

History[edit | edit source]

Thyrotropin alfa was first approved for medical use in the United States in 1998. It is marketed under the brand name Thyrogen by Genzyme.

See also[edit | edit source]

Thyrotropin alfa Resources
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Contributors: Bonnu, Prab R. Tumpati, MD