5F-CUMYL-PEGACLONE
5F-CUMYL-PEGACLONE is a synthetic cannabinoid that is also known as SGT-151. It is a potent agonist for the cannabinoid receptors, with Ki values of 0.1nM for CB1 and 0.5nM for CB2.
Chemistry[edit | edit source]
5F-CUMYL-PEGACLONE belongs to the chemical class of naphthoylindoles. The systematic name of this compound is 1-(5-fluoropentyl)-N-(2-phenylpropan-2-yl)-1H-indole-3-carboxamide. It is similar in structure to other synthetic cannabinoids such as 5F-ADB and 5F-AMB.
Pharmacology[edit | edit source]
As a synthetic cannabinoid, 5F-CUMYL-PEGACLONE acts as an agonist at the CB1 and CB2 receptors. The agonist activity at these receptors is believed to be responsible for the psychoactive and physiological effects of the compound.
Effects[edit | edit source]
The effects of 5F-CUMYL-PEGACLONE can vary greatly depending on the dose and the individual's tolerance to synthetic cannabinoids. Some reported effects include euphoria, relaxation, altered perception, and adverse effects such as anxiety, paranoia, and psychosis.
Legal Status[edit | edit source]
The legal status of 5F-CUMYL-PEGACLONE varies by country. In many places, it is classified as a controlled substance due to its potential for abuse and the lack of medical use.
See Also[edit | edit source]
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Contributors: Prab R. Tumpati, MD