Amiodarone
(Redirected from Amiodarons)
Amiodarone is a medication used in the treatment of various types of tachyarrhythmia, an abnormal fast rhythm of the heart. It is a class III antiarrhythmic agent and is used in situations where other medications are either not effective or are contraindicated.
Pharmacology[edit | edit source]
Amiodarone works by prolonging the duration of the action potential of cardiac tissue and by prolonging the refractory period of the heart's electrical conduction system. It achieves this by inhibiting potassium channels, which are responsible for repolarization of the heart following a heartbeat. This results in a slowing of the heart rate and a reduction in the occurrence of abnormal heart rhythms.
Medical uses[edit | edit source]
Amiodarone is primarily used to treat a variety of heart rhythm disorders such as ventricular tachycardia and ventricular fibrillation. It is also used in the treatment of wide complex tachycardia, as well as atrial fibrillation and paroxysmal supraventricular tachycardia. It is often used when other medications have failed to control the heart rhythm disorder.
Side effects[edit | edit source]
The use of Amiodarone can be associated with several side effects. These can include nausea, vomiting, constipation, and anorexia. More serious side effects can include pulmonary toxicity, thyroid dysfunction, and liver toxicity. Due to these potential side effects, monitoring is required during treatment with Amiodarone.
History[edit | edit source]
Amiodarone was initially developed in 1961 in Belgium. It was initially used as a treatment for angina, but its antiarrhythmic properties were discovered by chance. It was approved for medical use in the United States in 1985.
See also[edit | edit source]
List of antiarrhythmic agents:
- Amiodarone
- Disopyramide
- Dofetilide
- Dronedarone
- Flecainide
- Ivabradine
- Mexiletine
- Procainamide
- Propafenone
- Quinidine
| Amiodarone Resources | |
|---|---|
|
 |
Search WikiMD
Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro / Zepbound) available.
Advertise on WikiMD
|
WikiMD's Wellness Encyclopedia |
| Let Food Be Thy Medicine Medicine Thy Food - Hippocrates |
Translate this page: - East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
தமிழ்,
తెలుగు,
Urdu,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
বাংলা
European
español,
Deutsch,
français,
Greek,
português do Brasil,
polski,
română,
русский,
Nederlands,
norsk,
svenska,
suomi,
Italian
Middle Eastern & African
عربى,
Turkish,
Persian,
Hebrew,
Afrikaans,
isiZulu,
Kiswahili,
Other
Bulgarian,
Hungarian,
Czech,
Swedish,
മലയാളം,
मराठी,
ਪੰਜਾਬੀ,
ગુજરાતી,
Portuguese,
Ukrainian
Medical Disclaimer: WikiMD is not a substitute for professional medical advice. The information on WikiMD is provided as an information resource only, may be incorrect, outdated or misleading, and is not to be used or relied on for any diagnostic or treatment purposes. Please consult your health care provider before making any healthcare decisions or for guidance about a specific medical condition. WikiMD expressly disclaims responsibility, and shall have no liability, for any damages, loss, injury, or liability whatsoever suffered as a result of your reliance on the information contained in this site. By visiting this site you agree to the foregoing terms and conditions, which may from time to time be changed or supplemented by WikiMD. If you do not agree to the foregoing terms and conditions, you should not enter or use this site. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates Wikipedia, licensed under CC BY SA or similar.
Contributors: Prab R. Tumpati, MD
