Nystatin Topical
(Redirected from Candex)
What is Nystatin Topical?[edit | edit source]
- Nystatin Topical is a polyene antifungal antibiotic obtained from Streptomyces noursei used to treat fungal infections of the skin.
What are the uses of this medicine?[edit | edit source]
- Nystatin Topical is used in the treatment of cutaneous or mucocutaneous mycotic infections caused by Candida albicans and other susceptible Candida species.
- Nystatin Cream USP is not indicated for systemic, oral, intravaginal or ophthalmic use.
How does this medicine work?[edit | edit source]
- Nystatin is an antibiotic which is both fungistatic and fungicidal in vitro against a wide variety of yeasts and yeast-like fungi, including Candida albicans, C. parapsilosis, C. tropicalis, C. guilliermondi, C. pseudotropicalis, C. krusei, Torulopsis glabrata, Tricophyton rubrum, T. mentagrophytes.
- Nystatin acts by binding to sterols in the cell membrane of susceptible species resulting in a change in membrane permeability and the subsequent leakage of intracellular components.
- Nystatin exhibits no appreciable activity against bacteria, protozoa, or viruses.
Who Should Not Use this medicine ?[edit | edit source]
This medicine cannot be used in patients with:
- with a history of hypersensitivity to any of its components.
What drug interactions can this medicine cause?[edit | edit source]
- Tell your doctor and pharmacist what other prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take.
Is this medicine FDA approved?[edit | edit source]
- Nystatin was approved by the FDA in 1971 and is currently widely used in the treatment of superficial yeast infections and candida infections of the skin, mucous membranes and gastrointestinal tract, including oropharyngeal candidiasis.
How should this medicine be used?[edit | edit source]
Recommended dosage: Adults and Pediatric Patients (Neonates and Older):
- Apply liberally to affected areas twice daily or as indicated until healing is complete.
Administration:
- Nystatin comes as a cream, ointment and powder to apply to the skin.
- Nystatin cream and ointment is usually applied twice a day to the affected area. Nystatin powder is usually used two or three times a day.
- Use nystatin at around the same times every day.
- If you are using powder for infected feet, dust the powder inside your shoes and stockings as well as on your feet.
- Topical nystatin is only for use on the skin.
- Do not let nystatin get into your vagina, eyes, or mouth, and do not swallow the medication.
- Use nystatin as long as instructed by your doctor, even if you feel better. If you stop using nystatin too soon or skip doses, your infection may not be completely treated.
What are the dosage forms and brand names of this medicine?[edit | edit source]
This medicine is available in fallowing doasage form:
- As Nystatin Cream USP for topical use, contains 100,000 USP nystatin units per gram.
This medicine is available in fallowing brand namesː
- Barstatin Powder
- Candex Cream
- Mycostatin Cream
- Mycostatin Ointment
- Mycostatin Powder
- Mykinac Cream
- Mykinac Ointment
- Nilstat Cream
- Nilstat Ointment
- Nilstat Powder
- Nyamyc Powder
- Nystop Powder
What side effects can this medication cause?[edit | edit source]
The most common side effects of this medicine include:
What special precautions should I follow?[edit | edit source]
- Nystatin Cream USP should not be used for the treatment of systemic, oral, intravaginal or ophthalmic infections.
- Even if symptomatic relief occurs within the first few days of treatment, the patient should be advised not to interrupt or discontinue therapy until the prescribed course of treatment is completed.
- If symptoms of irritation develop, the patient should be advised to notify the physician promptly.
- It is not known whether Nystatin is excreted in human milk. Caution should be exercised when nystatin is prescribed for a nursing woman.
What to do in case of emergency/overdose?[edit | edit source]
- In case of overdose, call the poison control helpline of your country. In the United States, call 1-800-222-1222.
- Overdose related information is also available online at poisonhelp.org/help.
- In the event that the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services. In the United States, call 911.
Can this medicine be used in pregnancy?[edit | edit source]
- Category C.
- It is not known whether these preparations can cause fetal harm when used by a pregnant woman or can affect reproductive capacity.
- Nystatin topical preparations should be prescribed for a pregnant woman only if the potential benefit to the mother outweighs the potential risk to the fetus.
Can this medicine be used in children?[edit | edit source]
- Safety and effectiveness have been established in the pediatric population from birth to 16 years.
What are the active and inactive ingredients in this medicine?[edit | edit source]
Active ingredient:
- Nystatin
Inactive ingredients:
- emulsifying wax, glycerin, isopropyl myristate, lactic acid, purified water, sodium hydroxide, and sorbic acid.
Who manufactures and distributes this medicine?[edit | edit source]
Manufactured By:
- Perrigo
- Bronx, NY
Distributed By:
- Perrigo
- Allegan, MI
What should I know about storage and disposal of this medication?[edit | edit source]
- Store at 20-25°C (68-77°F).
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