Primary cutaneous aspergillosis

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Primary cutaneous aspergillosis
Synonyms N/A
Pronounce N/A
Specialty N/A
Symptoms Skin lesions, nodules, ulcers
Complications Systemic infection
Onset Rapid
Duration Variable
Types N/A
Causes Aspergillus species
Risks Immunocompromised state
Diagnosis Biopsy, culture
Differential diagnosis N/A
Prevention N/A
Treatment Antifungal medications
Medication N/A
Prognosis Variable
Frequency N/A
Deaths N/A


Primary cutaneous aspergillosis is a rare fungal infection of the skin caused by the Aspergillus species. It typically occurs in immunocompromised individuals, such as those undergoing chemotherapy, organ transplantation, or with HIV/AIDS.

Presentation[edit | edit source]

The condition presents with skin lesions that may appear as nodules, ulcers, or plaques. These lesions can be painful and may progress rapidly, especially in individuals with weakened immune systems.

Causes[edit | edit source]

Primary cutaneous aspergillosis is caused by direct inoculation of Aspergillus spores into the skin. This can occur through trauma, surgery, or the use of intravenous catheters. The most common species involved is Aspergillus fumigatus.

Diagnosis[edit | edit source]

Diagnosis is typically made through a combination of biopsy and culture of the affected skin. Histopathology may reveal characteristic fungal hyphae, and culture can identify the specific Aspergillus species.

Treatment[edit | edit source]

Treatment involves the use of antifungal medications, such as voriconazole or amphotericin B. In some cases, surgical debridement of the infected tissue may be necessary.

Prognosis[edit | edit source]

The prognosis of primary cutaneous aspergillosis varies depending on the patient's immune status and the timeliness of treatment. Early diagnosis and appropriate antifungal therapy can improve outcomes.

See also[edit | edit source]

References[edit | edit source]





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Contributors: Prab R. Tumpati, MD