Pyogenic liver abscess

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Pyogenic Liver Abscess[edit | edit source]

A large hepatic abscess marked on a CT scan.

A pyogenic liver abscess is a pus-filled cavity in the liver caused by a bacterial infection. It is a serious condition that requires prompt medical attention and treatment. The liver is a vital organ responsible for numerous functions, including detoxification, protein synthesis, and the production of biochemicals necessary for digestion.

Etiology[edit | edit source]

Pyogenic liver abscesses are most commonly caused by bacterial infections. The bacteria can reach the liver through the biliary tract, the portal vein, or by direct extension from a nearby infection. Common pathogens include Escherichia coli, Klebsiella pneumoniae, and Staphylococcus aureus.

Pathophysiology[edit | edit source]

The formation of a pyogenic liver abscess begins with the invasion of bacteria into the liver tissue. This invasion leads to an inflammatory response, resulting in the accumulation of pus and the formation of an abscess. The abscess can cause significant damage to liver tissue and impair liver function.

Clinical Presentation[edit | edit source]

Patients with a pyogenic liver abscess may present with a variety of symptoms, including:

Diagnosis[edit | edit source]

The diagnosis of a pyogenic liver abscess is typically made using imaging studies. Ultrasound and computed tomography (CT) scans are commonly used to visualize the abscess. Blood tests may show elevated white blood cell count and liver function tests.

Treatment[edit | edit source]

Treatment of a pyogenic liver abscess involves:

Prognosis[edit | edit source]

With appropriate treatment, the prognosis for patients with a pyogenic liver abscess is generally good. However, if left untreated, the condition can lead to serious complications, including sepsis and death.

Related Pages[edit | edit source]


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Contributors: Prab R. Tumpati, MD