Amanitins

From WikiMD's Wellness Encyclopedia

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Alpha-amanitin-Ball-and-Stick-Animation

What are amaninitins?[edit | edit source]

Amaninitis are cyclic peptides extracted from carpophores of various mushroom species.

Amanita flavipes
Amanita flavipes

Use in molecular genetics[edit | edit source]

They are potent inhibitors of RNA polymerases in most eukaryotic species, blocking the production of mRNA and protein synthesis.

Study of transcription[edit | edit source]

These peptides are important in the study of transcription.

Types[edit | edit source]

There are 4 main types of amanitins, of which α-Amanitin is the most popular. α-Amanitin β-Amanitin γ-Amanitin ε-Amanitin

Mushroom poisoning[edit | edit source]

Alpha-amanitin is the main toxin from the species Amanitia phalloides, poisonous if ingested by humans or animals.


Amanitins Resources
Wikipedia
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Contributors: Prab R. Tumpati, MD