9-Hydroxyhexahydrocannabinol

9-Hydroxyhexahydrocannabinol (9-OH-HHC) is a cannabinoid that is a metabolite of hexahydrocannabinol (HHC). It is less potent than its parent compound but still exhibits some of the same effects.

Chemistry

9-Hydroxyhexahydrocannabinol is a hydroxylated derivative of hexahydrocannabinol. The hydroxylation occurs at the 9 position, resulting in a compound with a hydroxyl group (-OH) attached to the carbon at the 9 position of the hexahydrocannabinol molecule.

Pharmacology

Like other cannabinoids, 9-OH-HHC interacts with the cannabinoid receptors in the body, specifically the CB1 and CB2 receptors. These receptors are part of the endocannabinoid system, which plays a role in a variety of physiological processes including pain sensation, mood, and memory.

9-OH-HHC is less potent than hexahydrocannabinol, but it still exhibits some of the same effects. These effects can include analgesia, relaxation, and changes in perception. However, the exact effects can vary depending on the dose and the individual's sensitivity to cannabinoids.

Metabolism

9-Hydroxyhexahydrocannabinol is a metabolite of hexahydrocannabinol, which means it is produced in the body during the metabolism of HHC. The exact metabolic pathway is not fully understood, but it is believed to involve the action of the enzyme cytochrome P450, which is responsible for the hydroxylation of many drugs and other substances in the body.

See also

• Cannabinoid
• Hexahydrocannabinol
• Endocannabinoid system
• Cytochrome P450

References

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