Vascularization

Vascularization refers to the formation of blood vessels in the body. It is a crucial process in the growth and development of organs and tissues. Vascularization is also important in the healing of wounds and in the formation of granulation tissue.

Types of Vascularization

There are two main types of vascularization: vasculogenesis and angiogenesis.

Vasculogenesis

Vasculogenesis is the process of blood vessel formation occurring by a de novo production of endothelial cells. This process occurs in embryos as they develop, but can also occur in adults during the growth of certain types of tumors.

Angiogenesis

Angiogenesis is the formation of new blood vessels from pre-existing vessels. This process is crucial during growth and development, as well as in wound healing and in the formation of granulation tissue. It is also a fundamental step in the transition of tumors from a benign state to a malignant one.

Role in Disease

Vascularization plays a significant role in the progression of diseases such as cancer, diabetes, and atherosclerosis. In cancer, for example, the growth and spread of tumors depend on the formation of new blood vessels, a process known as tumor angiogenesis.

See Also

• Blood vessel
• Endothelial cells
• Vasculogenesis
• Angiogenesis
• Cancer
• Diabetes
• Atherosclerosis

References

Vascularization Resources
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