Wedelolactone

Wedelolactone is a chemical compound that is classified as a coumestan. It is found in various plants, most notably in the Eclipta alba species, also known as false daisy. Wedelolactone has been studied for its potential medicinal properties, including anti-inflammatory, anti-cancer, and hepatoprotective effects.

Chemical Structure

Wedelolactone is a coumestan, a type of phytoestrogen. It has a unique structure that includes a fused three-ring system. The compound is named after the plant genus Wedelia, from which it was first isolated.

Sources

The primary natural source of wedelolactone is the plant Eclipta alba, also known as false daisy or bhringraj. This plant is native to India and other parts of Asia, and has been used in traditional medicine for centuries. Wedelolactone can also be found in other plants, such as Wedelia calendulacea and Wedelia chinensis.

Potential Medicinal Properties

Wedelolactone has been studied for its potential medicinal properties. Some of the key areas of research include:

Anti-inflammatory Effects

Wedelolactone has been shown to have anti-inflammatory properties. It inhibits the production of pro-inflammatory cytokines, which are substances that can cause inflammation in the body.

Anti-cancer Effects

Some studies have suggested that wedelolactone may have anti-cancer effects. It has been shown to induce apoptosis, or programmed cell death, in certain types of cancer cells.

Hepatoprotective Effects

Wedelolactone has been studied for its potential hepatoprotective effects. It may help to protect the liver from damage caused by toxins or disease.

Safety and Side Effects

While wedelolactone has potential medicinal properties, it is important to note that more research is needed to fully understand its safety and effectiveness. As with any substance, it can have side effects, especially when taken in large amounts. Always consult with a healthcare provider before starting any new treatment.

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Chemical structure of wedelolactone

See Also

• Eclipta alba
• Coumestan
• Phytoestrogen