Adenoid basal cell carcinoma

Adenoid Basal Cell Carcinoma (ABCC) is a rare variant of basal cell carcinoma (BCC), a type of skin cancer. It is characterized by its unique histological features and generally has a favorable prognosis.

Epidemiology

ABCC is a rare form of BCC, accounting for less than 1% of all BCC cases. It is more commonly found in older individuals, with a slight predilection for females.

Pathophysiology

ABCC is characterized by the presence of basaloid cells, which are arranged in a cribriform or adenoid pattern. These cells are typically found in the dermis and can extend into the subcutaneous tissue. The tumor cells are often surrounded by a dense fibrous stroma.

Clinical Presentation

Patients with ABCC typically present with a slow-growing, painless nodule or plaque. The lesion is often located on the head or neck, particularly on the face. The color of the lesion can vary from skin-colored to pink or red.

Diagnosis

The diagnosis of ABCC is primarily based on histopathological examination. A skin biopsy is typically performed, and the specimen is examined under a microscope. The characteristic histological features of ABCC include the presence of basaloid cells arranged in a cribriform or adenoid pattern.

Treatment

The primary treatment for ABCC is surgical excision. Mohs micrographic surgery is often the preferred method, as it allows for the complete removal of the tumor while sparing as much healthy tissue as possible. Other treatment options include radiation therapy and topical chemotherapy.

Prognosis

The prognosis for ABCC is generally favorable. The tumor is typically slow-growing and rarely metastasizes. However, recurrence can occur, particularly if the tumor is not completely excised.

See Also

• Basal cell carcinoma
• Skin cancer
• Mohs surgery

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