2C-O

2C-O is a psychedelic phenethylamine of the 2C family. It was first synthesized by Alexander Shulgin.

History

2C-O was first synthesized and documented by Alexander Shulgin. In his book PiHKAL, Shulgin lists the dosage range as 20–60 mg. 2C-O is described as similar in nature to mescaline, but with a longer duration of action.

Chemistry

2C-O, or 2,5-dimethoxy-4-(n)-propylphenethylamine, is a phenethylamine with a propyl group bound to the nitrogen of the phenethylamine backbone. It also contains two methoxy functional groups CH3O- which are attached to carbons R2 and R5 of the benzene ring. It is a colorless oil.

Pharmacology

Like other 2C-x related molecules, 2C-O likely acts as a 5-HT2A receptor agonist in the brain. This receptor is involved in the cognitive, perceptual, and mood effects of psychedelics.

Effects

The effects of 2C-O can vary greatly depending on the dosage, set and setting, and individual metabolism. However, common effects reported by users include visual hallucinations, euphoria, time distortion, and introspection. These effects are similar to other psychedelic phenethylamines.

Legal Status

As of 2021, 2C-O is not scheduled under the United Nations Convention on Psychotropic Substances. However, it may be considered illegal in some countries under analogue laws.

See Also

• 2C (psychedelics)
• Phenethylamine
• PiHKAL
• Alexander Shulgin

2C-O Resources
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