3,4-Methylenedioxy-N-propargylamphetamine
3,4-Methylenedioxy-N-propargylamphetamine (MDPL) is a psychedelic and entactogen of the amphetamine class. It is structurally related to MDMA (3,4-methylenedioxy-N-methylamphetamine) and is known for its psychoactive effects.
Chemical Structure[edit | edit source]
MDPL is characterized by the presence of a methylenedioxy group attached to the phenyl ring and a propargyl group attached to the nitrogen atom of the amphetamine backbone. This structural modification distinguishes it from other amphetamines and contributes to its unique pharmacological properties.
Pharmacology[edit | edit source]
MDPL acts primarily as a serotonin releasing agent, similar to other entactogens like MDMA. It increases the levels of serotonin in the synaptic cleft by promoting the release of serotonin from presynaptic neurons. This action is responsible for its mood-enhancing and empathogenic effects.
Effects[edit | edit source]
The effects of MDPL are similar to those of other entactogens, including increased empathy, euphoria, and altered sensory perception. Users may experience enhanced emotional connectivity and a sense of well-being. However, the specific effects can vary depending on the dose and individual differences.
Legal Status[edit | edit source]
The legal status of MDPL varies by country. In many jurisdictions, it is classified as a controlled substance due to its structural similarity to MDMA and its potential for abuse.
Related Pages[edit | edit source]
3,4-Methylenedioxy-N-propargylamphetamine[edit | edit source]
MDPL chemical structure
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Contributors: Prab R. Tumpati, MD
