BRINP3

From WikiMD's Wellness Encyclopedia

BRINP3 or BMP/Retnoid/Inducible Neural Specific 3 is a protein that in humans is encoded by the BRINP3 gene. It is also known as FAM5C (Family with sequence similarity 5, member C).

Function[edit | edit source]

The BRINP3 gene is a member of the BRINP family of genes. This family of genes is known to play a significant role in cellular differentiation and tissue development. The BRINP3 protein is expressed in various tissues, with the highest levels found in the brain and heart. It is believed to play a crucial role in neuronal differentiation and may also be involved in apoptosis.

Clinical Significance[edit | edit source]

Alterations in the BRINP3 gene have been associated with a variety of medical conditions. For instance, mutations in this gene have been linked to neurodevelopmental disorders, including autism and schizophrenia. Additionally, changes in the expression of BRINP3 have been observed in certain types of cancer, suggesting a potential role in tumor suppression.

Research[edit | edit source]

Research into the BRINP3 gene and its associated protein is ongoing. Current studies are focused on understanding the precise role of this gene in cellular differentiation and development, as well as its potential involvement in disease processes.

See Also[edit | edit source]


{{Navbox | name = Genes on human chromosome 4 | title = Genes on human chromosome 4 | listclass = hlist

| group1 = Locus 4p16.3 | list1 =

| group2 = Locus 4q21-q22 | list2 =

| group3 = Locus 4q25 | list3 =

| group4 = Locus 4q28.3 | list4 =

| group5 = Locus 4q31.21 | list5 =

| group6 = Locus 4q32-q35 | list6 =

| group7 = Other notable genes | list7 =

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Contributors: Prab R. Tumpati, MD