Cephalothin sodium

Cephalothin Sodium is a type of antibiotic that belongs to the cephalosporin class. It is used in the treatment of various bacterial infections, including those of the respiratory tract, urinary tract, skin, and soft tissue. Cephalothin Sodium is also used in surgical prophylaxis to prevent postoperative infections.

Pharmacology

Cephalothin Sodium works by inhibiting the synthesis of the bacterial cell wall, leading to cell death. It is a bactericidal antibiotic, meaning it kills bacteria rather than merely inhibiting their growth. Cephalothin Sodium is effective against a wide range of Gram-positive bacteria and some Gram-negative bacteria.

Administration and Dosage

Cephalothin Sodium is typically administered intravenously or intramuscularly. The dosage varies depending on the severity and type of infection, as well as the patient's age, weight, and kidney function. It is important to complete the full course of treatment to prevent the development of antibiotic resistance.

Side Effects and Precautions

Common side effects of Cephalothin Sodium include nausea, vomiting, diarrhea, and rash. Serious side effects, although rare, can include anaphylaxis, kidney damage, and blood disorders. Patients with a history of allergy to cephalosporins or penicillins should use Cephalothin Sodium with caution, as cross-reactivity may occur.

Interactions

Cephalothin Sodium may interact with other medications, including probenecid, aminoglycosides, and oral contraceptives. It is important to inform healthcare providers of all medications being taken to avoid potential interactions.

See Also

• Cephalosporin
• Antibiotic resistance
• Bacterial cell wall