Pain

From WikiMD's Wellness Encyclopedia

(Redirected from Breakthrough pain)

Pain is a complex, multifaceted phenomenon that is both a sensory and an emotional experience associated with actual or potential tissue damage. Stemming from the Latin word "poena" signifying a penalty or a fine, pain involves a combination of physical sensation and psychological interpretation.[1]

Neck pain 2

Distinction Between Pain and Nociception[edit | edit source]

Hyperalgesia and allodynia

As per the International Association for the Study of Pain (IASP), it's essential to discern between the concepts of pain and nociception. While 'pain' encompasses the subjective experience, typically accompanying nociception, it can also emerge absent any stimulus, encapsulating the emotional response. 'Nociception', however, is a neurophysiological term representing specific activity in nerve pathways. It serves as the transmission system for physiological pain but does not encompass psychological pain. Nociceptive pathways can transmit signals traditionally identified as 'painful', but these signals are not always interpreted as such.[2]

The Importance of Pain[edit | edit source]

Despite the discomfort it brings, pain functions as a vital part of the body's defense mechanism. It forms a component of a swift warning relay system instructing the central nervous system's motor neurons to minimize perceived physical damage. Conditions like Congenital insensitivity to pain or Congenital Analgesia, where the ability to experience pain is absent, can lead to various health complications.[3]

Common Forms of Pain[edit | edit source]

Headaches and back pain are the two most frequently reported forms of pain in the U.S. Pain is also specifically used to denote a painful uterine contraction occurring during childbirth.[4]

Pain Classification[edit | edit source]

Pain can be classified according to various criteria, such as duration (acute or chronic), source (neuropathic, nociceptive, psychogenic), and location (localized or generalized).

Acute and Chronic Pain[edit | edit source]

Acute pain typically follows an injury and dissipates once the injury heals or is effectively treated. It acts as a biological alarm to warn us of potential bodily harm.[5]

Chronic pain, on the other hand, persists beyond the expected period of healing, lasting for months to years. It's often associated with conditions such as arthritis, cancer, and neuralgia.[6]

Neuropathic, Nociceptive, and Psychogenic Pain[edit | edit source]

Neuropathic pain arises from injury to the nervous system itself, such as in cases of diabetic neuropathy or postherpetic neuralgia. It is often described as a burning or shooting pain.[7]

Nociceptive pain is a response to tissue injury or inflammation, as in cuts, sprains, or bone fractures. This kind of pain is often sharp, aching, or throbbing in nature.[8]

Psychogenic pain, also referred to as psychalgia or somatoform pain, is pain caused, increased, or prolonged by mental, emotional, or behavioral factors.[9]

Pain Management[edit | edit source]

Pain management can be complex and requires a multifaceted approach. This may include pharmacological interventions such as analgesics, non-steroidal anti-inflammatory drugs (NSAIDs), and opioids, as well as non-pharmacological interventions like physiotherapy, psychological therapy, and alternative treatments such as acupuncture.[10]

Pain Resources


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  1. "Table 30. Severe headache or migraine, low back pain, and neck pain among adults aged 18 and over, by selected characteristics: United States, 2016" (PDF). Center for Disease Control and Prevention. Retrieved 23 September 2021.

Contributors: Prab R. Tumpati, MD