Norclostebol acetate

Norclostebol acetate is a synthetic androgen and anabolic steroid and a derivative of testosterone. It is more specifically a derivative of nandrolone (19-nortestosterone) and is also known as 19-norandrost-4-en-17β-ol-3-one 17β-acetate. Norclostebol acetate is a prodrug of norclostebol, and is described as a weak androgen and anabolic with minimal estrogenic and no progestogenic activity.

History[edit | edit source]

Norclostebol acetate was first described in the literature in 1956 and was introduced for medical use by 1959. It was developed by Organon, a Dutch pharmaceutical company, and was marketed under the brand name Lentaron Depot.

Medical uses[edit | edit source]

Norclostebol acetate has been used in the treatment of breast cancer and osteoporosis. It has also been used to promote weight gain and muscle growth in patients with malnutrition or other conditions that cause weight loss, such as cancer or AIDS.

Side effects[edit | edit source]

The side effects of norclostebol acetate are similar to those of other anabolic steroids, and can include acne, hair loss, voice deepening, and masculinization in women. It can also have adverse effects on cholesterol levels and cardiovascular health.

Pharmacology[edit | edit source]

Norclostebol acetate is a prodrug of norclostebol, which is the active form of the drug. It is metabolized in the body by esterases into norclostebol.

Society and culture[edit | edit source]

Norclostebol acetate has been used in the world of bodybuilding and sports doping. It is on the World Anti-Doping Agency's list of prohibited substances, and is therefore banned from use in most competitive sports.