Magaldrate

Magaldrate

Magaldrate is an antacid drug used for the treatment of gastrointestinal disorders such as peptic ulcer disease and gastroesophageal reflux disease (GERD). It is a complex compound that is formed by the reaction of aluminum hydroxide and magnesium hydroxide with sulfuric acid. The resulting product is a salt that has both buffering and adsorbent properties.

Mechanism of Action

Magaldrate works by neutralizing gastric acid in the stomach. It reacts with the acid to produce a salt that is less harmful to the stomach lining. This helps to reduce the symptoms of heartburn and indigestion associated with excess stomach acid. In addition, magaldrate has adsorbent properties, meaning it can bind to and remove certain substances from the body. This can be beneficial in the treatment of certain types of poisoning.

Side Effects

Like all medications, magaldrate can cause side effects. These may include constipation, diarrhea, and stomach cramps. In rare cases, it can cause more serious side effects such as kidney stones or hypercalcemia, a condition characterized by high levels of calcium in the blood.

Interactions

Magaldrate can interact with other medications, including certain types of antibiotics, iron supplements, and bisphosphonates, a class of drugs used to treat osteoporosis. It is important to inform your healthcare provider of all medications you are taking before starting treatment with magaldrate.

Contraindications

Magaldrate should not be used in individuals with kidney disease or those with a history of allergic reactions to aluminum or magnesium. It should also be used with caution in individuals with heart disease or high blood pressure, as it can cause fluid retention.

See Also

• Antacids
• Gastrointestinal disorders
• Peptic ulcer disease
• Gastroesophageal reflux disease

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