Dehydrochlormethyltestosterone
Dehydrochlormethyltestosterone (also known as Turinabol) is a synthetic anabolic steroid developed in the 1960s by Jenapharm, an East German pharmaceutical company.
History[edit | edit source]
Dehydrochlormethyltestosterone was first described in 1962. It was developed as a means to build muscle mass and strength in a short period of time. It was widely used by East German athletes in the 1970s and 1980s, often without their knowledge, in a state-sponsored doping program known as State Plan 14.25.
Pharmacology[edit | edit source]
Dehydrochlormethyltestosterone is a derivative of testosterone, modified to enhance its anabolic properties and reduce its androgenic ones. It is classified as a Schedule III controlled substance under the Controlled Substances Act in the United States.
Medical Use[edit | edit source]
While Dehydrochlormethyltestosterone was originally developed for medical use, it is no longer used therapeutically. It was previously used to treat conditions that cause a loss of lean muscle mass.
Side Effects[edit | edit source]
The side effects of Dehydrochlormethyltestosterone include liver damage, cardiovascular disease, and in men, gynecomastia (breast development) and testicular atrophy (shrinkage). In women, it can cause virilization (development of male characteristics).
Doping in Sports[edit | edit source]
Dehydrochlormethyltestosterone has a history of use in sports doping. It was the steroid of choice in the East German doping program, and has been implicated in more recent doping scandals, including those involving Russian athletes at the 2014 Winter Olympics in Sochi.
See Also[edit | edit source]
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Contributors: Prab R. Tumpati, MD