Nandrolone undecanoate

Nandrolone undecanoate is a synthetic anabolic steroid that is derived from testosterone. It is used in the treatment of osteoporosis, anemia, and some forms of neoplasia including breast cancer, and also acts as a progestin-based contraceptive.

Chemistry

Nandrolone undecanoate, also known as 19-nortestosterone 17β-undecanoate, is a synthetic estrane steroid and a derivative of testosterone. It is more specifically a derivative of 19-nortestosterone (nandrolone). The steroid is a lipophilic compound that is transported in the bloodstream and stored in fat depots.

Pharmacology

Nandrolone undecanoate is a prodrug of nandrolone, being converted in the body by esterases into nandrolone, which is then metabolized by enzymes in the liver. The drug has a very long duration of action, with a half-life of up to one month.

Medical uses

Nandrolone undecanoate is used in the treatment of osteoporosis, anemia, and some forms of neoplasia including breast cancer. It is also used as a progestin-based contraceptive in combination with an estrogen.

Side effects

The side effects of nandrolone undecanoate are similar to those of other anabolic steroids. These can include acne, gynecomastia, edema, weight gain, insomnia, mood changes, hair loss, libido changes, and liver damage.

See also

• List of androgens/anabolic steroids
• List of progestogen esters