Androstanolone propionate

From WikiMD's Wellness Encyclopedia

Androstanolone Propionate, also known as dihydrotestosterone propionate or DHT propionate, is a synthetic androgenic steroid and a derivative of dihydrotestosterone (DHT). It is used in the medical field primarily for the treatment of male hypogonadism, a condition where the body does not produce enough testosterone. This compound is known for its potent androgenic effects with minimal anabolic activity, making it unique among synthetic steroids.

Medical Uses[edit | edit source]

Androstanolone Propionate is utilized in the treatment of conditions associated with low testosterone levels in men. These conditions include:

  • Delayed puberty in boys
  • Hypogonadism or testosterone deficiency
  • Certain types of impotence
  • Breast cancer in women, under specific circumstances

It is administered through intramuscular injection and works by supplementing or replacing the natural testosterone, which is normally produced in the testes.

Pharmacology[edit | edit source]

Mechanism of Action[edit | edit source]

Androstanolone Propionate functions by binding to and activating the androgen receptor (AR), which is a type of nuclear receptor that is activated by binding any of the androgenic hormones, such as testosterone or dihydrotestosterone. This binding leads to the activation of gene expression that is responsible for the male phenotype and male sexual characteristics.

Pharmacokinetics[edit | edit source]

The propionate ester of Androstanolone allows for a slower release of the hormone from the site of injection, extending its duration of action. This means that Androstanolone Propionate does not need to be administered as frequently as other forms of testosterone replacement therapy.

Side Effects[edit | edit source]

As with any androgenic steroid, Androstanolone Propionate can have side effects, which may include:

  • Acne
  • Hair loss
  • Prostate enlargement
  • Masculinization in women (when used for breast cancer treatment)
  • Alterations in cholesterol levels and other blood lipids
  • Liver toxicity, though this is less common compared to other anabolic steroids

Patients are advised to monitor for these side effects under the guidance of a healthcare provider.

Contraindications[edit | edit source]

Androstanolone Propionate should not be used in individuals with:

  • Known or suspected prostate or breast cancer in men
  • Liver disease
  • Severe heart conditions
  • Pregnancy or breastfeeding in women

See Also[edit | edit source]

References[edit | edit source]



Contributors: Prab R. Tumpati, MD