Vasculitis
(Redirected from Leukocytoclasis)
Inflammation of blood vessels
Vasculitis is a group of disorders characterized by inflammation of the blood vessels. This inflammation can cause the walls of the blood vessels to thicken, which reduces the width of the passageway through the vessel. If blood flow is restricted, it can result in organ and tissue damage. Vasculitis can affect any of the body's blood vessels, including arteries, veins, and capillaries.
Classification[edit | edit source]
Vasculitis is classified based on the size of the blood vessels affected:
Large vessel vasculitis[edit | edit source]
Medium vessel vasculitis[edit | edit source]
Small vessel vasculitis[edit | edit source]
- Granulomatosis with polyangiitis
- Microscopic polyangiitis
- Eosinophilic granulomatosis with polyangiitis (formerly known as Churg-Strauss syndrome)
Signs and symptoms[edit | edit source]
The symptoms of vasculitis vary greatly and depend on the organs affected. Common symptoms include:
- Fever
- Fatigue
- Weight loss
- Muscle and joint pain
- Loss of appetite
Causes[edit | edit source]
The exact cause of vasculitis is often unknown. It can be triggered by infections, medications, or other diseases. Some forms of vasculitis are associated with autoimmune disorders, where the immune system mistakenly attacks the body's own tissues.
Diagnosis[edit | edit source]
Diagnosis of vasculitis typically involves a combination of:
Treatment[edit | edit source]
Treatment depends on the type and severity of vasculitis. Common treatments include:
- Corticosteroids to reduce inflammation
- Immunosuppressive drugs
- Biologic agents
Prognosis[edit | edit source]
The prognosis for vasculitis varies. Some forms are mild and resolve on their own, while others can be life-threatening without treatment. Early diagnosis and treatment are crucial for a better outcome.
Related pages[edit | edit source]
Gallery[edit | edit source]
Henoch-Sch�nlein purpura, a type of small vessel vasculitis
Histopathology of eosinophilic granulomatosis with polyangiitis
FDG PET-CT scan showing vasculitis
| Vasculitis Resources | |
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Vasculitis[edit | edit source]
Henoch-Schönlein purpura (HSP) vasculitis
Churg-Strauss syndrome under very high magnification
Vasculitis as seen on FDG PET-CT
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Contributors: Prab R. Tumpati, MD
