Docefrez

From WikiMD's Wellness Encyclopedia




Docefrez is a chemotherapy medication used primarily in the treatment of various types of cancer. It is a formulation of docetaxel, which is a taxane used to inhibit cell division by disrupting the microtubular network within the cell. Docefrez is administered intravenously and is commonly used in the treatment of breast cancer, non-small cell lung cancer, prostate cancer, gastric cancer, and head and neck cancer.

Mechanism of Action[edit | edit source]

Docefrez works by stabilizing the microtubules in the cell, preventing their disassembly which is necessary for cell division. This action inhibits the mitotic process, leading to cell death. The drug specifically targets rapidly dividing cells, a characteristic of cancer cells, making it effective in slowing down or stopping the growth of tumors.

Indications[edit | edit source]

Docefrez is indicated for the treatment of:

Administration[edit | edit source]

Docefrez is administered through an intravenous infusion. The dosage and frequency of administration depend on the type of cancer being treated, the stage of the disease, and the patient's overall health and response to the treatment.

Side Effects[edit | edit source]

Common side effects of Docefrez include:

Serious side effects may include severe allergic reactions, fluid retention, and neuropathy.

Precautions[edit | edit source]

Patients receiving Docefrez should be monitored for signs of bone marrow suppression, liver function, and allergic reactions. Pre-medication with corticosteroids is often recommended to reduce the risk of hypersensitivity reactions and fluid retention.

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Contributors: Prab R. Tumpati, MD