Acrodermatitis chronica atrophicans

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Acrodermatitis chronica atrophicans is a skin condition, and as the name suggests, it leads to chronic atrophy of the skin and polyneuropathy.

Bacterial infection[edit | edit source]

This progressive skin condition caused by spirochete Borrelia afzelii, and to some lesser degree, B. afzelii, and Borrelia garinii.

Clinical presentation[edit | edit source]

The skin rash is seen most commonly on extremities.

Stages[edit | edit source]

  • It begins with an inflammatory stage and later with an atrophic phase.
  • Sclerotic skin plaques may also develop.
  • ACA progresses the skin begins to wrinkle.

Testing[edit | edit source]

1)Screening test- IgM and IgG ELISA 2) If 1 is positive or there is high clinical suspicion in spite of Elisa being negative than confirmatory test - Western Blot.

Other methods[edit | edit source]

Microscopy and culture (in modified Kelly's medium) of skin biopsy or blood samples.

Treatment[edit | edit source]

Doxycycline[edit | edit source]

Treatment consists of antibiotics including doxycycline and penicillin for up to four weeks in the acute case and sometimes longer.

See also[edit | edit source]



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