Acrodermatitis chronica atrophicans
Acrodermatitis chronica atrophicans is a skin condition, and as the name suggests, it leads to chronic atrophy of the skin and polyneuropathy.
Bacterial infection[edit | edit source]
This progressive skin condition caused by spirochete Borrelia afzelii, and to some lesser degree, B. afzelii, and Borrelia garinii.
Clinical presentation[edit | edit source]
The skin rash is seen most commonly on extremities.
Stages[edit | edit source]
- It begins with an inflammatory stage and later with an atrophic phase.
- Sclerotic skin plaques may also develop.
- ACA progresses the skin begins to wrinkle.
Testing[edit | edit source]
1)Screening test- IgM and IgG ELISA 2) If 1 is positive or there is high clinical suspicion in spite of Elisa being negative than confirmatory test - Western Blot.
Other methods[edit | edit source]
Microscopy and culture (in modified Kelly's medium) of skin biopsy or blood samples.
Treatment[edit | edit source]
Doxycycline[edit | edit source]
Treatment consists of antibiotics including doxycycline and penicillin for up to four weeks in the acute case and sometimes longer.
See also[edit | edit source]
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Credits:Most images are courtesy of Wikimedia commons, and templates Wikipedia, licensed under CC BY SA or similar.Contributors: Prab R. Tumpati, MD