Nemorexant

Nemorexant (also known as E2006) is a drug that is used in the treatment of insomnia. It is an orexin receptor antagonist, which means it works by blocking the action of a hormone called orexin that regulates wakefulness.

History

Nemorexant was developed by Eisai, a Japanese pharmaceutical company. The drug was first introduced in the market in 2019. It was developed as a response to the need for more effective treatments for insomnia, a condition that affects millions of people worldwide.

Mechanism of Action

Nemorexant works by blocking the action of orexin, a hormone that is produced in the hypothalamus and is involved in the regulation of sleep and wakefulness. By blocking the action of orexin, Nemorexant helps to promote sleep and reduce wakefulness.

Uses

Nemorexant is used in the treatment of insomnia. It is particularly effective in cases where insomnia is caused by an overactive orexin system, such as in cases of narcolepsy.

Side Effects

Like all drugs, Nemorexant can cause side effects. These can include drowsiness, dizziness, and dry mouth. In rare cases, it can also cause more serious side effects such as abnormal dreams and sleep paralysis.

See Also

• Orexin receptor antagonist
• Insomnia
• Eisai (company)

References

• Eisai. (2019). Eisai's Insomnia Drug Nemorexant Receives Approval in Japan. Retrieved from Eisai website.
• National Sleep Foundation. (2019). Insomnia. Retrieved from National Sleep Foundation website.