Trental

Trental is a medication used in the treatment of peripheral artery disease (PAD) and intermittent claudication. The active ingredient in Trental is Pentoxifylline, which works by improving blood flow and reducing inflammation in the blood vessels.

Uses

Trental is primarily used to treat peripheral artery disease and intermittent claudication. It can help to increase walking distance in individuals with these conditions. It may also be used off-label for other conditions as determined by a healthcare provider.

Mechanism of Action

The active ingredient in Trental, pentoxifylline, is a xanthine derivative. It works by increasing the flexibility of red blood cells, which allows them to pass through narrowed blood vessels more easily. It also reduces the viscosity of blood, further improving blood flow. Additionally, pentoxifylline has anti-inflammatory effects.

Side Effects

Common side effects of Trental include nausea, vomiting, dizziness, and headache. More serious side effects can include irregular heartbeat, chest pain, and signs of an allergic reaction.

Interactions

Trental can interact with other medications, including anticoagulants and antiplatelet drugs. It is important to discuss all medications and supplements with a healthcare provider before starting Trental.

Precautions

Before starting Trental, individuals should discuss their medical history with their healthcare provider, especially any history of heart disease, kidney disease, or recent surgery. Trental should be used with caution in individuals with these conditions.

See Also

• Peripheral artery disease
• Intermittent claudication
• Pentoxifylline

Trental Resources
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