Bread loafing
| Bread Loafing | |
|---|---|
| |
| Synonyms | |
| Pronounce | N/A |
| Specialty | Pathology |
| Symptoms | |
| Complications | |
| Onset | |
| Duration | |
| Types | |
| Causes | Surgical excision |
| Risks | |
| Diagnosis | Histopathology |
| Differential diagnosis | |
| Prevention | |
| Treatment | |
| Medication | |
| Prognosis | |
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Bread loafing is a term used in pathology to describe a method of processing tissue samples during biopsy or surgical excision. This technique involves slicing the tissue into parallel sections, similar to slicing a loaf of bread, before further examination under a microscope. Bread loafing is commonly employed in the examination of larger tissue specimens, where it is crucial to assess the architecture and margins of the sample comprehensively.
Technique[edit | edit source]
The bread loafing technique involves the systematic slicing of tissue specimens at regular intervals to ensure that the entire specimen is adequately represented in the slices prepared for histopathology. This method allows pathologists to examine the relationship between different tissue components and to assess for the presence of disease at the margins of the specimen.
Applications[edit | edit source]
Bread loafing is particularly useful in the examination of excisional biopsies of the skin, such as those performed for melanoma or other skin cancers. It is also employed in the assessment of surgical margins in the resection of tumors, to ensure that no malignant cells are left at the edges of the excised tissue.
Advantages[edit | edit source]
- Comprehensive Examination: Allows for a thorough examination of the specimen's architecture and margins.
- Disease Assessment: Facilitates the assessment of the presence and extent of disease within the tissue.
Limitations[edit | edit source]
- Sampling Error: There is a risk of missing small foci of disease if they are not included in the slices taken for examination.
- Time-Consuming: The process can be time-consuming, especially for large specimens.
See Also[edit | edit source]
References[edit | edit source]
Resources[edit source]
Latest articles - Bread loafing
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Source: Data courtesy of the U.S. National Library of Medicine. Since the data might have changed, please query MeSH on Bread loafing for any updates.
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