AC-261066

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AC-261066 is a synthetic nonsteroidal selective androgen receptor modulator (SARM) that has been studied for its potential use in treating conditions such as muscle wasting and osteoporosis. It is known for its ability to selectively target androgen receptors in muscle and bone tissues, potentially offering the benefits of anabolic steroids without the undesirable side effects associated with steroid use.

Mechanism of Action

AC-261066 functions by binding to the androgen receptor (AR) with high affinity. Upon binding, it modulates the receptor's activity, promoting anabolic effects in muscle and bone tissues while minimizing androgenic effects in other tissues such as the prostate. This selective action is what distinguishes SARMs like AC-261066 from traditional anabolic steroids, which tend to affect all androgen-responsive tissues indiscriminately.

Pharmacokinetics

The pharmacokinetic profile of AC-261066 involves its absorption, distribution, metabolism, and excretion. While specific data on AC-261066 is limited, SARMs generally exhibit good oral bioavailability and a favorable half-life, allowing for convenient dosing regimens. The metabolism of AC-261066 is likely to involve hepatic pathways, with excretion primarily through the renal system.

Potential Applications

AC-261066 has been investigated for several potential therapeutic applications:

• Muscle Wasting: Due to its anabolic effects, AC-261066 may help in preserving or increasing muscle mass in patients suffering from muscle wasting conditions such as cachexia or sarcopenia.
• Osteoporosis: By promoting bone density, AC-261066 could be beneficial in treating or preventing osteoporosis, a condition characterized by weak and brittle bones.
• Hypogonadism: As a SARM, AC-261066 might offer an alternative to testosterone replacement therapy in men with low testosterone levels, providing anabolic benefits without significant androgenic side effects.

Research and Development

Research on AC-261066 is ongoing, with studies focusing on its efficacy, safety, and potential side effects. Preclinical studies have shown promising results, but further clinical trials are necessary to fully understand its therapeutic potential and safety profile.

Safety and Side Effects

While SARMs like AC-261066 are designed to minimize side effects, potential adverse effects may still occur. These could include hormonal imbalances, liver toxicity, and cardiovascular issues. Long-term safety data is currently lacking, necessitating caution in its use.

Legal Status

The legal status of AC-261066 varies by country. In some regions, it may be classified as a research chemical, while in others, it might be regulated as a controlled substance. It is important for researchers and users to be aware of the legal implications of possessing and using AC-261066.

Also see

• Selective androgen receptor modulator
• Anabolic steroid
• Muscle wasting
• Osteoporosis
• Hypogonadism