Artane
Artane | |
---|---|
[[File:|frameless|220px|alt=|]] | |
INN | |
Drug class | |
Routes of administration | Oral |
Pregnancy category | |
Bioavailability | |
Metabolism | Hepatic |
Elimination half-life | 6-10 hours |
Excretion | Renal |
Legal status | |
CAS Number | 52-49-3 |
PubChem | 5566 |
DrugBank | DB00376 |
ChemSpider | 5366 |
KEGG | D00381 |
Artane is the brand name for the drug Trihexyphenidyl, which is an anticholinergic medication used primarily to treat Parkinson's disease and extrapyramidal symptoms caused by antipsychotic medications.
Medical Uses[edit | edit source]
Artane is used to manage symptoms of Parkinson's disease, such as tremor, rigidity, and bradykinesia. It is also effective in treating extrapyramidal side effects associated with the use of antipsychotic drugs.
Mechanism of Action[edit | edit source]
Artane works by blocking acetylcholine receptors in the central nervous system, which helps to restore the balance between acetylcholine and dopamine in the brain. This action helps to reduce the symptoms of Parkinson's disease and drug-induced parkinsonism.
Side Effects[edit | edit source]
Common side effects of Artane include dry mouth, blurred vision, constipation, urinary retention, and tachycardia. In some cases, it may cause confusion, hallucinations, or memory impairment, especially in older adults.
Contraindications[edit | edit source]
Artane is contraindicated in patients with narrow-angle glaucoma, obstructive gastrointestinal disease, and urinary retention. Caution is advised in patients with cardiovascular disease and elderly patients.
Interactions[edit | edit source]
Artane may interact with other anticholinergic drugs, antihistamines, and tricyclic antidepressants, potentially increasing the risk of side effects. It may also interact with levodopa, used in the treatment of Parkinson's disease.
Dosage[edit | edit source]
The dosage of Artane is individualized based on the patient's response and tolerance. It is typically started at a low dose and gradually increased. The usual adult dose ranges from 1 mg to 15 mg per day, divided into 3 to 4 doses.
See Also[edit | edit source]
References[edit | edit source]
External Links[edit | edit source]
Search WikiMD
Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro / Zepbound) available.
Advertise on WikiMD
WikiMD's Wellness Encyclopedia |
Let Food Be Thy Medicine Medicine Thy Food - Hippocrates |
Translate this page: - East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
தமிழ்,
తెలుగు,
Urdu,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
বাংলা
European
español,
Deutsch,
français,
Greek,
português do Brasil,
polski,
română,
русский,
Nederlands,
norsk,
svenska,
suomi,
Italian
Middle Eastern & African
عربى,
Turkish,
Persian,
Hebrew,
Afrikaans,
isiZulu,
Kiswahili,
Other
Bulgarian,
Hungarian,
Czech,
Swedish,
മലയാളം,
मराठी,
ਪੰਜਾਬੀ,
ગુજરાતી,
Portuguese,
Ukrainian
Medical Disclaimer: WikiMD is not a substitute for professional medical advice. The information on WikiMD is provided as an information resource only, may be incorrect, outdated or misleading, and is not to be used or relied on for any diagnostic or treatment purposes. Please consult your health care provider before making any healthcare decisions or for guidance about a specific medical condition. WikiMD expressly disclaims responsibility, and shall have no liability, for any damages, loss, injury, or liability whatsoever suffered as a result of your reliance on the information contained in this site. By visiting this site you agree to the foregoing terms and conditions, which may from time to time be changed or supplemented by WikiMD. If you do not agree to the foregoing terms and conditions, you should not enter or use this site. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates, categories Wikipedia, licensed under CC BY SA or similar.
Contributors: Prab R. Tumpati, MD