Aclidinium bromide/formoterol

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What Is aclidinium bromide and formoterol fumarte ?[edit | edit source]

Aclidinium bromide.svg
Formoterol structure.svg



What are the uses of this medicine?[edit | edit source]


How does this medicine work?[edit | edit source]


Who Should Not Use this medicine ?[edit | edit source]

This medicine cannot be used in:

  • In patients with Severe hypersensitivity to milk proteins
  • In patients with hypersensitivity to aclidinium bromide, formoterol fumarate, or to any component of the product


Is this medicine FDA approved?[edit | edit source]

  • This combination has initial U.S. Approval in 2019.


How should this medicine be used?[edit | edit source]

  • The recommended dose of this medicine is one oral inhalation of 400 mcg/12 mcg, twice daily (once in the morning and once in the evening).
  • Do not take more than one inhalation twice daily.


What are the dosage forms and brand names of this medicine?[edit | edit source]

This medicine is available in fallowing doasage form:

  • This combination is available as inhalation Powder
  • It is a breath-actuated multi-dose dry powder inhaler metering 400 mcg of aclidinium bromide and 12 mcg of formoterol fumarate per actuation.


What side effects can this medication cause?[edit | edit source]

Common possible side effects of this medicine include:

Possible serious side effects, may include:


What special precautions should I follow?[edit | edit source]

  • Do not initiate to treat acute symptoms of COPD
  • Do not use in combination with an additional medicine containing a LABA because of risk of overdose.
  • If paradoxical bronchospasm occurs, discontinue the medication and institute alternative therapy.
  • Use with caution in patients with cardiovascular disorders.
  • Use with caution in patients with convulsive disorders, thyrotoxicosis, diabetes mellitus and ketoacidosis.
  • Always be alert with hypokalemia and hyperglycemia.
  • Use with caution in patients with narrow-angle glaucoma.
  • Worsening urinary retention may occur with this medication.


What to do in case of emergency/overdose?[edit | edit source]

  • The most common symptoms of overdosage include blurred vision, dry mouth, nausea, muscle spasms, tremor, headache, palpitations, and systolic hypertension.
  • Treatment of overdosage consists of discontinuation of Duaklir Pressair together with institution of appropriate symptomatic and/or supportive therapy.


Can this medicine be used in pregnancy?[edit | edit source]

  • There are no adequate and well-controlled studies of Duaklir Pressair or its individual components, formoterol fumarate or aclidinium bromide, in pregnant women.


Can this medicine be used in children?[edit | edit source]

  • This medication is not indicated for use in children.
  • The safety and effectiveness of Duaklir Pressair in the pediatric population have not been established.


What should I know about storage and disposal of this medication?[edit | edit source]

  • Store Duaklir Pressair in a dry place at 20°C-25°C (68°F-77°F); excursions permitted to 15-30°C (59-86°F) .
  • Do not store the inhaler on a vibrating surface.
  • The Pressair inhaler should be stored inside the sealed bag and only be opened immediately before use.
  • Throw away the bag and the desiccant sachet.
  • Throw away (dispose of) the Pressair inhaler after the marking “0” with a red background shows in the middle of the dose indicator, when the device is empty and locks out, or 2 months after the date you opened the sealed bag that the inhaler comes in, whichever comes first.
  • Keep out of reach of children.



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